Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501681 | 0.79 | CHEK1 (0.34) | KDM4E | |
| SCHEMBL23344391 | 0.78 | LMNA (0.46) | LMNASMN1; SMN2GAAMAPTALDH1A1 | |
| Ipexidine SCHEMBL11468017 | 0.75 | GNAI3 (0.52) | SMN1; SMN2GAATP53USP2KDM4E | |
| SCHEMBL11468097 | 0.69 | SIGMAR1 (0.52) | SMN1; SMN2GAAALDH1A1DRD2 | |
| SCHEMBL11575634 | 0.68 | USP2 (0.52) | LMNASMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL11501942 | 0.68 | TP53 (0.56) | SMN1; SMN2MAPTTP53DRD4 | |
| SCHEMBL10721796 | 0.66 | DRD4 (0.65) | LMNASMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL11574769 | 0.66 | SIGMAR1 (0.61) | MAPTALDH1A1TP53DRD4DRD2 | |
| SCHEMBL11726248 | 0.66 | LMNA (0.48) | LMNASMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL3265179 | 0.65 | SMN1; SMN2 (0.53) | LMNASMN1; SMN2GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110328-A | Bis-carbamylguanidinoazaalkane antimicrobial compounds | COOPER LABORATORIES, INC. (US) | 1978-08-29 | — | — | US | claimed |
| US-4209624-A | Process for preparing substituted bis(amidinoureas) | COOPER LABORATORIES, INC. (US) | 1980-06-24 | — | — | US | disclosed |