SCHEMBL23352201

SCHEMBL23352201

CS(=O)(=O)c1ccc(Cc2cnc(Cl)s2)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.47
LMNA P02545 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 2/20 0.42
LOXL2 Q9Y4K0 3/20 0.41
LOX P28300 2/20 0.41
TSHR P16473 1/20 0.41
PTGS2 P35354 2/20 0.40
POLB P06746 1/20 0.40
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
EPHX2 P34913 1/20 0.40
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
MAPT P10636 1/20 0.38
FFAR2 O15552 1/20 0.38
PTGS1 P23219 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20929520 0.82 LMNA (0.49) KMT2ALMNAL3MBTL1MEN1LOXL2
SCHEMBL20929533 0.75 EPHX2 (0.67) KMT2ALMNAL3MBTL1TDP1MEN1
SCHEMBL17410524 0.74 LMNA (0.61) KMT2ALMNAL3MBTL1TDP1MEN1
SCHEMBL20929556 0.74 L3MBTL1 (0.45) KMT2ALMNAL3MBTL1TDP1MEN1
SCHEMBL24604285 0.73 L3MBTL1 (0.63) KMT2ALMNAL3MBTL1TDP1MEN1
SCHEMBL13231429 0.73 ENPP2 (0.54) LMNAPTGS2
SCHEMBL28725053 0.72 PTGS2 (0.41) KMT2AL3MBTL1TDP1MEN1LOXL2
SCHEMBL3536702 0.71 KMT2A (0.56) KMT2ALMNAL3MBTL1TDP1MEN1
SCHEMBL23352198 0.70 ADRB2 (0.47) KMT2ALMNAL3MBTL1TDP1MEN1
SCHEMBL23352202 0.70 PTGS2 (0.40) KMT2ALMNAMEN1LOXL2LOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11459321-B2 Broad spectrum antiviral compositions and methods EVRYS BIO, LLC (US) 2022-10-04 US disclosed
US-20210139475-A1 Broad Spectrum Antiviral Compositions and Methods EVRYS BIO, LLC (US) 2021-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11459321-B2 Broad spectrum antiviral compositions and methods IRF3, MAVS, ZC3HAV1 KMT2A 2059/4885LMNA 2718/4885L3MBTL1 3947/4885
US-20210139475-A1 Broad Spectrum Antiviral Compositions and Methods MAVS, IRF3, ZC3HAV1 KMT2A 2333/4885LMNA 3185/4885L3MBTL1 3640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.