Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.41 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2337315 | 0.77 | G6PD (0.40) | MEN1KMT2AKCNMA1GAAMAPT | |
| SCHEMBL826757 | 0.76 | KDR (0.48) | DHODHACLYTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2341169 | 0.73 | TAS1R3 (0.38) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL2858561 | 0.73 | BRAF (0.55) | ACLYTAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL14833067 | 0.65 | PNMT (0.47) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL23417746 | 0.64 | TSHR (0.51) | MEN1KMT2ARAB9AMAPTTSHR | |
| SCHEMBL21814318 | 0.63 | MEN1 (0.70) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL953306 | 0.62 | CES2 (0.37) | MEN1KMT2AGAA | |
| SCHEMBL25899692 | 0.62 | RAB9A (0.50) | MEN1KMT2ARAB9ATP53USP2 | |
| SCHEMBL21678086 | 0.62 | ALDH1A1 (0.48) | MEN1KMT2ARAB9ANR1H4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358689-A1 | Benzothiazole derivatives as anticancer agents | Takeda Pharmaceutical Company Limited (JP) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010064722-A1 | BENZOTHIAZOLE DERIVATIVES AS ANTICANCER AGENTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-10 | — | — | WO | disclosed |