Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 5/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3702549 | 0.92 | LPAR1 (0.39) | P2RX3PTGS2LPAR1LPAR2LPAR3 | |
| SCHEMBL3705375 | 0.91 | TP53 (0.37) | P2RX3PTGS2KDM4EALDH1A1HPGD | |
| SCHEMBL3700510 | 0.89 | LPAR1 (0.36) | LPAR1LPAR2LPAR3KDM4EALDH1A1 | |
| SCHEMBL3714445 | 0.88 | LPAR1 (0.38) | LPAR1LPAR2LPAR3KDM4EALDH1A1 | |
| SCHEMBL2336634 | 0.88 | LPAR1 (0.43) | LPAR1LPAR2LPAR3KDM4EALDH1A1 | |
| SCHEMBL3708634 | 0.86 | ALDH1A1 (0.42) | LPAR1LPAR2LPAR3ALDH1A1L3MBTL1 | |
| SCHEMBL2338062 | 0.85 | LPAR1 (0.38) | EDNRBEDNRALPAR1LPAR2LPAR3 | |
| SCHEMBL3700609 | 0.84 | LPAR1 (0.46) | LPAR1LPAR2LPAR3KDM4EALDH1A1 | |
| SCHEMBL3707844 | 0.83 | L3MBTL1 (0.38) | LPAR1LPAR2LPAR3ALDH1A1SMN1; SMN2 | |
| SCHEMBL3712290 | 0.83 | NR3C1 (0.38) | P2RX3PTGS2LPAR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |