Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 4/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23354199 | 0.98 | APOBEC3A (0.40) | APOBEC3AAPOBEC3GSCDALDH1A1LMNA | |
| SCHEMBL5725062 | 0.81 | APOBEC3A (0.41) | APOBEC3AAPOBEC3GLMNAMEN1PABPC1 | |
| Bromide SCHEMBL7114981 | 0.80 | APOBEC3A (0.40) | APOBEC3AAPOBEC3GMEN1PABPC1KMT2A | |
| SCHEMBL15601778 | 0.79 | LMNA (0.46) | APOBEC3AAPOBEC3GSCDALDH1A1LMNA | |
| SCHEMBL14177821 | 0.77 | APOBEC3A (0.38) | APOBEC3AAPOBEC3GLMNASMN1; SMN2 | |
| SCHEMBL23354271 | 0.77 | EGLN1 (0.40) | APOBEC3AAPOBEC3GLMNACTDSP1EGLN1 | |
| SCHEMBL5726080 | 0.76 | BCAT2 (0.44) | APOBEC3AAPOBEC3GLMNAMEN1PABPC1 | |
| SCHEMBL5725359 | 0.76 | APOBEC3A (0.42) | APOBEC3AAPOBEC3GALDH1A1LMNAKMT2A | |
| SCHEMBL23367000 | 0.74 | APOBEC3A (0.41) | APOBEC3AAPOBEC3GALDH1A1LMNAKDM4E | |
| SCHEMBL5727138 | 0.73 | ALDH1A1 (0.48) | APOBEC3AAPOBEC3GALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027346-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-01-26 | — | — | US | disclosed |
| EP-3822268-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2021-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230027346-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | ADAMTS7, MMP7, ADAM17 | APOBEC3A 545/4885APOBEC3G 602/4885SCD 3511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.