Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | ADAMTS7 | Q9UKP4 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23385052 | 0.75 | ADAMTS7 (0.41) | HDAC1ADAMTS7NPC1RAB9ANTRK1 | |
| SCHEMBL23367473 | 0.72 | HDAC1 (0.49) | HDAC1ADAMTS7NPC1RAB9ANTRK1 | |
| SCHEMBL23384731 | 0.68 | ADAMTS7 (0.41) | HDAC1ADAMTS7NPC1RAB9ANTRK1 | |
| SCHEMBL6464483 | 0.66 | HDAC1 (0.55) | HDAC1ADAMTS7NPC1RAB9ANTRK1 | |
| SCHEMBL23367286 | 0.65 | LMNA (0.41) | NPC1RAB9A | |
| SCHEMBL13543694 | 0.64 | P2RX7 (0.46) | HDAC1ADAMTS7NPC1RAB9ANTRK1 | |
| SCHEMBL29873601 | 0.63 | ADAMTS7 (0.63) | HDAC1ADAMTS7 | |
| SCHEMBL23354726 | 0.63 | ADAMTS7 (0.63) | HDAC1ADAMTS7 | |
| SCHEMBL23354853 | 0.63 | ADAMTS7 (0.66) | HDAC1ADAMTS7NPC1RAB9A | |
| SCHEMBL23367365 | 0.63 | HDAC1 (0.41) | HDAC1ADAMTS7NPC1RAB9ANTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822265-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer AG (DE) | 2021-05-19 | — | — | EP | disclosed |