Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814514 | 0.75 | P2RX7 (0.62) | P2RX7ALDH1A1TSHRKMT2ALMNA | |
| SCHEMBL23354899 | 0.72 | ALDH1A1 (0.52) | ALDH1A1KMT2AHTTMAPK14LMNA | |
| SCHEMBL23367388 | 0.71 | P2RX7 (0.42) | P2RX7ALDH1A1MGLLKMT2AHTT | |
| SCHEMBL24938358 | 0.70 | MAPK14 (0.35) | ALDH1A1TSHRMGLLKMT2AHTT | |
| SCHEMBL28056728 | 0.68 | P2RX7 (0.59) | P2RX7ALDH1A1TSHRMGLLFLT3 | |
| SCHEMBL31568323 | 0.68 | L3MBTL1 (0.35) | P2RX7ALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL4550926 | 0.68 | FLT3 (0.44) | ALDH1A1TSHRMGLLKMT2ALMNA | |
| SCHEMBL16141027 | 0.68 | KMT2A (0.44) | ALDH1A1TSHRMGLLKMT2AHTT | |
| SCHEMBL23354892 | 0.67 | CYP1A2 (0.46) | ALDH1A1TSHRKMT2ALMNAKDM4E | |
| SCHEMBL3327427 | 0.67 | ALDH1A1 (0.46) | ALDH1A1TSHRMGLLKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822265-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer AG (DE) | 2021-05-19 | — | — | EP | disclosed |