Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ATP4A | P20648 | 1/20 | 0.31 |
| ▸ | ATP4B | P51164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23354899 | 0.72 | ALDH1A1 (0.52) | MAPK14SMN1; SMN2TP53ALDH1A1KMT2A | |
| SCHEMBL23367361 | 0.70 | P2RX7 (0.37) | MAPK14SMN1; SMN2TP53ALDH1A1KMT2A | |
| SCHEMBL4550926 | 0.68 | FLT3 (0.44) | SMN1; SMN2ALDH1A1KMT2AMEN1MGLL | |
| SCHEMBL16141027 | 0.68 | KMT2A (0.44) | SMN1; SMN2TP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL23354892 | 0.67 | CYP1A2 (0.46) | ALDH1A1KMT2AHPGDTSHR | |
| SCHEMBL18719287 | 0.66 | NPC1 (0.52) | SMN1; SMN2ALDH1A1KMT2AMEN1MGLL | |
| SCHEMBL23367562 | 0.66 | P2RX7 (0.35) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14886184 | 0.63 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1KMT2AMEN1MGLL | |
| SCHEMBL28536416 | 0.63 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1MGLLHPGDHTT | |
| SCHEMBL23400221 | 0.61 | MAPK14 (0.48) | MAPK14SMN1; SMN2TP53ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027985-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230027985-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | ADAMTS7, MMP7, ADAMTS1 | MAPK14 2445/4885SMN1; SMN2 3772/4885TP53 4354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.