Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15418298 | 0.93 | OPRM1 (0.42) | DNM1TSHRTDP1OPRM1CA1 | |
| SCHEMBL11262415 | 0.91 | OPRM1 (0.41) | DNM1TSHROPRM1ADH1BADH1C | |
| SCHEMBL5933020 | 0.90 | DNM1 (0.38) | DNM1ALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL20938972 | 0.84 | TDP1 (0.37) | TSHRTDP1ADRB2PTGS2OPRK1 | |
| SCHEMBL22863409 | 0.83 | ALDH1A1 (0.38) | DNM1ALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL20055670 | 0.81 | ALDH1A1 (0.37) | DNM1ALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL18991560 | 0.80 | DNM1 (0.35) | DNM1ALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL22268163 | 0.78 | ALDH1A1 (0.34) | DNM1ALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL18884674 | 0.77 | DNM1 (0.36) | DNM1ALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL21654996 | 0.76 | ALDH1A1 (0.37) | DNM1ALDH1A1TSHRCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210147422-A1 | ANTIMICROBIALS AND METHODS OF MAKING AND USING SAME | MELINTA THERAPEUTICS, INC. | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147422-A1 | ANTIMICROBIALS AND METHODS OF MAKING AND USING SAME | LPO, MPO, OAT | DNM1 670/4885ALDH1A1 1224/4885TSHR 4002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.