Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 8/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23422712 | 0.90 | MEN1 (0.33) | CYP3A4TSHRNR4A1ALDH1A1MAPK1 | |
| SCHEMBL30838571 | 0.84 | CYP3A4 (0.37) | CYP3A4TSHRNR4A1ALDH1A1MAPK1 | |
| SCHEMBL23407747 | 0.78 | THRB (0.37) | CYP3A4TSHRNR4A1ALDH1A1MAPK1 | |
| SCHEMBL23391539 | 0.78 | CYP3A4 (0.41) | CYP3A4TSHRNR4A1ALDH1A1MAPK1 | |
| SCHEMBL3190381 | 0.77 | TTR (0.55) | CYP3A4TSHRALDH1A1MAPK1THRB | |
| SCHEMBL273483 | 0.76 | NR4A1 (0.61) | CYP3A4TSHRNR4A1ALDH1A1MAPK1 | |
| SCHEMBL6912094 | 0.71 | THRA (0.45) | TSHRTHRBTHRA | |
| SCHEMBL5385598 | 0.70 | THRB (0.49) | ALDH1A1THRBTHRA | |
| SCHEMBL7192417 | 0.70 | MAOA (0.59) | CYP3A4TSHRNR4A1ALDH1A1MAPK1 | |
| SCHEMBL23391600 | 0.69 | CA1 (0.40) | CYP3A4TSHRNR4A1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195505-B | Inhibitors of metallo-beta-lactamase produced by multi-drug resistant bacteria and methods of making the same | 明知大学校产学协力团 | 2024-04-05 | — | — | CN | disclosed |
| EP-4063373-A1 | NOVEL METALLO-BETA-LACTAMASE INHIBITOR CREATED IN MULTI-DRUG RESISTANT BACTERIA, AND PREPARATION METHOD THEREFOR | Myongji University Industry and Academia Cooperation Foundation (KR) | 2022-09-28 | — | — | EP | disclosed |
| US-11395829-B2 | Inhibitors of metallo-beta-lactamases produced by multidrug-resistant bacteria | MYONGJI UNIVERSITY INDUSTRY AND ACADEMIA COOPERATION FOUNDATION (KR) | 2022-07-26 | — | — | US | disclosed |
| US-11395829-B2 | Inhibitors of metallo-beta-lactamases produced by multidrug-resistant bacteria | MYONGJI UNIVERSITY INDUSTRY AND ACADEMIA COOPERATION FOUNDATION (KR) | 2022-07-26 | — | — | US | disclosed |
| CN-113195505-A | Inhibitors of metallo-beta-lactamase produced by multi-drug resistant bacteria and methods of preparing the same | 明知大学校产学协力团 | 2021-07-30 | — | — | CN | disclosed |
| CN-113195505-A | Inhibitors of metallo-beta-lactamase produced by multi-drug resistant bacteria and methods of preparing the same | 明知大学校产学协力团 | 2021-07-30 | — | — | CN | disclosed |
| US-20210154216-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES PRODUCED BY MULTIDRUG-RESISTANT BACTERIA | MYONGJI UNIVERSITY INDUSTRY AND ACADEMIA COOPERATION FOUNDATION (KR) | 2021-05-27 | — | — | US | disclosed |
| US-20210154216-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES PRODUCED BY MULTIDRUG-RESISTANT BACTERIA | MYONGJI UNIVERSITY INDUSTRY AND ACADEMIA COOPERATION FOUNDATION (KR) | 2021-05-27 | — | — | US | disclosed |
| WO-2021101030-A1 | NOVEL METALLO-BETA-LACTAMASE INHIBITOR CREATED IN MULTI-DRUG RESISTANT BACTERIA, AND PREPARATION METHOD THEREFOR | 명지대학교 산학협력단 | 2021-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210154216-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES PRODUCED BY MULTIDRUG-RESISTANT BACTERIA | MANBA, MGAM, GUSB | CYP3A4 513/4885TSHR 4181/4885NR4A1 2515/4885 |
| US-11395829-B2 | Inhibitors of metallo-beta-lactamases produced by multidrug-resistant bacteria | MANBA, MGAM, GUSB | CYP3A4 513/4885TSHR 4181/4885NR4A1 2515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.