Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2756025 | 0.94 | MAPK1 (0.43) | TDP1MAPK1L3MBTL1TSHRALDH1A1 | |
| SCHEMBL234126 | 0.89 | MAOB (0.47) | KMT2AMAOBLMNAMAPTHPGD | |
| SCHEMBL3265205 | 0.86 | KMT2A (0.40) | TDP1MAPK1L3MBTL1TSHRALDH1A1 | |
| SCHEMBL1008532 | 0.82 | PTPN1 (0.48) | ALDH1A1KMT2AMEN1MAOBLMNA | |
| SCHEMBL15300298 | 0.82 | MAOB (0.43) | TSHRKMT2AMEN1NPC1MAOB | |
| SCHEMBL237424 | 0.82 | MAOB (0.48) | ALDH1A1MAOBLMNAMAPTHPGD | |
| SCHEMBL1634331 | 0.82 | TDP1 (0.52) | TDP1L3MBTL1TSHRALDH1A1KMT2A | |
| SCHEMBL1135054 | 0.81 | THRA (0.44) | TDP1ALDH1A1KMT2AMAOBLMNA | |
| SCHEMBL1009039 | 0.81 | TDP1 (0.44) | TDP1MAPK1L3MBTL1TSHRALDH1A1 | |
| SCHEMBL2090098 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KMT2AMAOBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703991-B2 | Synthesis of (phenylalkyloxy)phenyl-oxobutanoic acids | WELLSTAT THERAPEUTICS CORPORATION (US) | 2014-04-22 | — | — | US | claimed |
| US-20120004442-A1 | SYNTHESIS OF (PHENYLALKYLOXY)PHENYL-OXOBUTANOIC ACIDS | WELLSTAT THERAPEUTICS CORPORATION (US) | 2012-01-05 | — | — | US | claimed |
| EP-2365746-A1 | SYNTHESIS OF (PHENYLALKYLOXY)PHENYL-OXOBUTANOIC ACIDS | Wellstat Therapeutics Corporation (US) | 2011-09-21 | — | — | EP | claimed |
| WO-2010053910-A1 | SYNTHESIS OF (PHENYLALKYLOXY)PHENYL-OXOBUTANOIC ACIDS | WELLSTAT THERAPEUTICS CORPORATION (US) | 2010-05-14 | — | — | WO | claimed |
| US-8703991-B2 | Synthesis of (phenylalkyloxy)phenyl-oxobutanoic acids | WELLSTAT THERAPEUTICS CORPORATION (US) | 2014-04-22 | — | — | US | disclosed |
| US-20120004442-A1 | SYNTHESIS OF (PHENYLALKYLOXY)PHENYL-OXOBUTANOIC ACIDS | WELLSTAT THERAPEUTICS CORPORATION (US) | 2012-01-05 | — | — | US | disclosed |
| EP-2365746-A1 | SYNTHESIS OF (PHENYLALKYLOXY)PHENYL-OXOBUTANOIC ACIDS | Wellstat Therapeutics Corporation (US) | 2011-09-21 | — | — | EP | disclosed |
| WO-2010053910-A1 | SYNTHESIS OF (PHENYLALKYLOXY)PHENYL-OXOBUTANOIC ACIDS | WELLSTAT THERAPEUTICS CORPORATION (US) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010053910-A1 | SYNTHESIS OF (PHENYLALKYLOXY)PHENYL-OXOBUTANOIC ACIDS | WELLSTAT THERAPEUTICS CORPORATION (US) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004442-A1 | SYNTHESIS OF (PHENYLALKYLOXY)PHENYL-OXOBUTANOIC ACIDS | PGD, HPD, MLYCD | TDP1 3194/4885MAPK1 2882/4885L3MBTL1 1451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.