SCHEMBL3265205

SCHEMBL3265205

CCOC(=O)C(C=O)CC(=O)c1cccc(OCc2c(C)cccc2C)c1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
MAOB P27338 3/20 0.39
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
SLC22A12 Q96S37 1/20 0.38
PTPN1 P18031 1/20 0.38
L3MBTL1 Q9Y468 3/20 0.37
TSHR P16473 2/20 0.37
MAPK1 P28482 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 2/20 0.37
USP2 O75604 1/20 0.37
GAA P10253 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
NR4A2 P43354 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3268473 0.89 MAOB (0.42) KMT2AMAOBHPGDSMN1; SMN2LMNA
SCHEMBL234222 0.86 TDP1 (0.45) KMT2AMEN1NPC1MAOBHPGD
SCHEMBL2756025 0.83 MAPK1 (0.43) KMT2AMEN1NPC1MAOBHPGD
SCHEMBL234126 0.80 MAOB (0.47) KMT2AMAOBHPGDSMN1; SMN2LMNA
SCHEMBL1008532 0.79 PTPN1 (0.48) KMT2AMEN1MAOBHPGDSMN1; SMN2
SCHEMBL15300298 0.78 MAOB (0.43) KMT2AMEN1NPC1MAOBHPGD
SCHEMBL1634331 0.78 TDP1 (0.52) KMT2AMEN1NPC1MAOBSMN1; SMN2
SCHEMBL1135054 0.78 THRA (0.44) KMT2AMAOBHPGDSMN1; SMN2LMNA
SCHEMBL2090098 0.76 ALDH1A1 (0.43) KMT2AMAOBHPGDSMN1; SMN2LMNA
SCHEMBL237424 0.76 MAOB (0.48) MAOBHPGDSMN1; SMN2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120004442-A1 SYNTHESIS OF (PHENYLALKYLOXY)PHENYL-OXOBUTANOIC ACIDS WELLSTAT THERAPEUTICS CORPORATION (US) 2012-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004442-A1 SYNTHESIS OF (PHENYLALKYLOXY)PHENYL-OXOBUTANOIC ACIDS PGD, HPD, MLYCD KMT2A 2740/4885MEN1 3664/4885NPC1 2775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.