Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.63 |
| ▸ | RELA | Q04206 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603497 | 0.85 | ALDH1A1 (0.74) | CHEK2ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL20982796 | 0.85 | MEN1 (0.57) | ALDH1A1SMN1; SMN2MAPTNPC1TP53 | |
| SCHEMBL1233401 | 0.84 | TOP1 (0.57) | CHEK2ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL16393847 | 0.82 | TRPV1 (0.57) | CHEK2ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL1232791 | 0.81 | PLG (0.51) | CHEK2ACHEPLGPLAUHDAC6 | |
| SCHEMBL16586563 | 0.80 | PLG (0.50) | CHEK2ACHEPLGPLAUHDAC6 | |
| SCHEMBL16586719 | 0.80 | PLG (0.52) | CHEK2ACHEPLGPLAUHDAC6 | |
| SCHEMBL2562072 | 0.79 | NPBWR1 (0.59) | CHEK2ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL4396538 | 0.78 | NPC1 (0.60) | CHEK2ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL22452317 | 0.77 | NPC1 (0.70) | CHEK2ALDH1A1SMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021105887-A1 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | EMP BIOTECH GMBH (DE) | 2021-06-03 | — | — | WO | disclosed |
| US-20210155657-A1 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | EMP BIOTECH GMBH (DE) | 2021-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210155657-A1 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | ADAR, SSBP1, POLRMT | CHEK2 2394/4885ALDH1A1 4165/4885SMN1; SMN2 1103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.