Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 9/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13989010 | 0.76 | KMT2A (0.36) | FEN1ERCC5MAPT | |
| SCHEMBL4716880 | 0.75 | FEN1 (0.41) | FEN1ERCC5 | |
| SCHEMBL1522723 | 0.73 | KMT2A (0.56) | FEN1ERCC5 | |
| SCHEMBL1522285 | 0.73 | ALDH1A1 (0.39) | FEN1LMNAMAPT | |
| SCHEMBL5259729 | 0.73 | DHFR (0.46) | — | |
| SCHEMBL1522918 | 0.72 | LMNA (0.39) | FEN1LMNAMAPT | |
| SCHEMBL1523122 | 0.72 | KMT2A (0.36) | FEN1ERCC5MAPTRXFP1 | |
| SCHEMBL1523552 | 0.72 | FEN1 (0.33) | FEN1ERCC5LMNA | |
| SCHEMBL1522863 | 0.71 | FEN1 (0.54) | FEN1ERCC5 | |
| SCHEMBL1522821 | 0.70 | ALDH1A1 (0.36) | FEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361913-A1 | Anti-infective agents | Abbott Laboratories (US) | 2011-08-31 | — | — | EP | disclosed |
| US-20050075331-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2005-04-07 | — | — | US | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| US-20040097492-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-20 | — | — | US | disclosed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097492-A1 | Anti-infective agents | POLR1C, RPL5, POLB | FEN1 1213/4885ERCC5 2973/4885LMNA 3232/4885 |
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | FEN1 1213/4885ERCC5 2973/4885LMNA 3232/4885 |
| US-20050075331-A1 | Anti-infective agents | RPL35, POLI, POLRMT | FEN1 1845/4885ERCC5 3596/4885LMNA 4225/4885 |
| US-20040087577-A1 | Anti-infective agents | POLR1C, RPL5, POLB | FEN1 1213/4885ERCC5 2973/4885LMNA 3232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.