SCHEMBL2344710

SCHEMBL2344710

O=C(Cc1ccc(O)c(O)c1)N(O)Cc1ccc(F)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.49
POLB P06746 2/20 0.49
APEX1 P27695 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
KDM4E B2RXH2 2/20 0.49
MAPT P10636 2/20 0.49
HSD17B10 Q99714 2/20 0.49
RGS12 O14924 1/20 0.49
GAA P10253 1/20 0.49
HPGD P15428 1/20 0.49
TSHR P16473 1/20 0.49
NFKB1 P19838 1/20 0.49
THPO P40225 1/20 0.49
BLM P54132 1/20 0.49
GNAI1 P63096 1/20 0.49
PMP22 Q01453 1/20 0.49
HIF1A Q16665 1/20 0.49
RIPK1 Q13546 1/20 0.46
ALOX5 P09917 1/20 0.43
BCHE P06276 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2335482 0.83 ESR1 (0.53) LMNAPOLBAPEX1TDP1GAA
SCHEMBL2341738 0.77 LMNA (0.47) LMNAPOLBKDM4EMAPTGAA
SCHEMBL2339858 0.75 PTPN1 (0.42) POLBAPEX1TDP1RIPK1ALOX5
SCHEMBL2343977 0.75 ALOX5 (0.57) POLBAPEX1TDP1GAAHPGD
SCHEMBL9313893 0.72 KDM4E (0.60) LMNAPOLBAPEX1TDP1KDM4E
Hydrochloric Acid SCHEMBL28989826 0.70 KDM4E (0.58) LMNAPOLBAPEX1TDP1KDM4E
SCHEMBL10948201 0.69 TSHR (0.56) LMNAPOLBAPEX1TDP1KDM4E
SCHEMBL27772568 0.69 ALOX15 (0.61) LMNAAPEX1TDP1KDM4EMAPT
SCHEMBL22982989 0.68 KDM4E (0.72) LMNAPOLBAPEX1TDP1KDM4E
SCHEMBL31618868 0.68 KDM4E (0.72) LMNAPOLBAPEX1TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9210928-B2 Plant development control composition SYNGENTA CROP PROTECTION, LLC (US) 2015-12-15 US disclosed
US-20110301028-A1 PLANT DEVELOPMENT CONTROL COMPOSITION SYNGENTA CROP PROTECTION, LLC (US) 2011-12-08 US disclosed
EP-2358197-A2 PLANT DEVELOPMENT CONTROL COMPOSITION Syngenta Participations AG (CH) 2011-08-24 EP disclosed
WO-2010055316-A2 PLANT DEVELOPMENT CONTROL COMPOSITION THE UNIVERSITY OF WARWICK (GB) 2010-05-20 WO disclosed
WO-2010055310-A1 HERBICIDAL COMPOSITIONS THE UNIVERSITY OF WARWICK (GB) 2010-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110301028-A1 PLANT DEVELOPMENT CONTROL COMPOSITION MSL1, OXSR1, OSR1 LMNA 4679/4885POLB 2166/4885APEX1 4040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.