Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | EBP | Q15125 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23453791 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP1A2MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL12863835 | 0.79 | ALDH1A1 (0.50) | SMN1; SMN2CYP1A2MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL23453869 | 0.76 | MEN1 (0.48) | ALDH1A1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL19034570 | 0.72 | ALDH1A1 (0.55) | SMN1; SMN2CYP1A2MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL1855324 | 0.72 | CYP1A2 (0.53) | SMN1; SMN2CYP1A2MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL19034571 | 0.71 | DGKA (0.50) | SMN1; SMN2CYP1A2MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL12863854 | 0.71 | PAOX (0.45) | SMN1; SMN2ALDH1A1L3MBTL1TSHRHRH3 | |
| SCHEMBL11593239 | 0.70 | SIGMAR1 (0.50) | SMN1; SMN2CYP1A2MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL15027866 | 0.70 | ALDH1A1 (0.56) | SMN1; SMN2CYP1A2ALDH1A1L3MBTL1TSHR | |
| SCHEMBL15027795 | 0.70 | ALDH1A1 (0.56) | SMN1; SMN2CYP1A2ALDH1A1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210169804-A1 | NANOMATERIALS | GUIDE THERAPEUTICS, LLC | 2021-06-10 | — | — | US | disclosed |
| WO-2021113365-A1 | NANOMATERIALS | GUIDE THERAPEUTICS, INC. (US) | 2021-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210169804-A1 | NANOMATERIALS | POLRMT, PHOSPHO1, FABP1 | SMN1; SMN2 1827/4885CYP1A2 4347/4885MAPK1 4711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.