Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 8/20 | 0.70 |
| ▸ | PGR | P06401 | 4/20 | 0.70 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | AR | P10275 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SHBG | P04278 | 1/20 | 0.53 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MLNR | O43193 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221482 | 0.90 | NR3C2 (0.86) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL29060653 | 0.90 | NR3C2 (0.86) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL122186 | 0.90 | NR3C2 (0.79) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL18506544 | 0.86 | NR3C2 (0.68) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL10597451 | 0.84 | NR3C2 (0.87) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL10597455 | 0.84 | NR3C2 (0.87) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL1030719 | 0.83 | NR3C2 (0.74) | NR3C2PGRNR3C1HIF1AKMT2A | |
| Hydrocortisone Butyrate SCHEMBL14473210 | 0.83 | NR3C2 (1.00) | NR3C2PGRNR3C1HIF1AKMT2A | |
| Hydrocortisone Butyrate SCHEMBL111478 | 0.83 | NR3C2 (1.00) | NR3C2PGRNR3C1HIF1AKMT2A | |
| Hydrocortisone Butyrate SCHEMBL14936050 | 0.83 | NR3C2 (1.00) | NR3C2PGRNR3C1HIF1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240130980-A1 | COMPOSITIONS FOR TREATING ACNE AND DERMATOLOGICAL CONDITIONS | Ilera Derm LLC | 2024-04-25 | — | — | US | disclosed |
| US-11931452-B2 | Topical compositions containing rofecoxib and methods of making and using the same | JF PHARMA TECH LLC (US) | 2024-03-19 | — | — | US | disclosed |
| US-11890260-B2 | Compositions for treating acne and dermatological conditions | Ilera Derm LLC (US) | 2024-02-06 | — | — | US | disclosed |
| EP-4153306-A1 | COMPOSITIONS FOR TREATING ACNE AND DERMATOLOGICAL CONDITIONS | Ilera Derm LLC (US) | 2023-03-29 | — | — | EP | disclosed |
| US-20230025960-A1 | TOPICAL COMPOSITIONS CONTAINING ROSE OIL AND CANNABIDIOL AND METHODS OF MAKING AND USING THE SAME | JLABS Beauty LLC (US) | 2023-01-26 | — | — | US | disclosed |
| US-11260023-B2 | Topical compositions containing rofecoxib and methods of making and using the same | BRIORI BIOTECH, LLC (US) | 2022-03-01 | — | — | US | disclosed |
| US-20210361591-A1 | COMPOSITIONS FOR TREATING ACNE AND DERMATOLOGICAL CONDITIONS | Ilera Derm LLC | 2021-11-25 | — | — | US | disclosed |
| WO-2021237214-A1 | COMPOSITIONS FOR TREATING ACNE AND DERMATOLOGICAL CONDITIONS | Ilera Derm LLC (US) | 2021-11-25 | — | — | WO | disclosed |
| US-20210220259-A1 | TOPICAL COMPOSITIONS CONTAINING ROFECOXIB AND METHODS OF MAKING AND USING THE SAME | ESTRATO PHARMA INC | 2021-07-22 | — | — | US | disclosed |
| WO-2021113083-A1 | TOPICAL COMPOSITIONS CONTAINING ROSE OIL AND CANNABIDIOL AND METHODS OF MAKING AND USING THE SAME | JLABS Beauty LLC (US) | 2021-06-10 | — | — | WO | disclosed |
| US-20210169759-A1 | TOPICAL COMPOSITIONS CONTAINING ROSE OIL AND CANNABIDIOL AND METHODS OF MAKING AND USING THE SAME | JLABS Beauty LLC | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11890260-B2 | Compositions for treating acne and dermatological conditions | COQ8A, ATP5ME, AGK | NR3C2 4001/4885PGR 590/4885NR3C1 3071/4885 |
| US-20230025960-A1 | TOPICAL COMPOSITIONS CONTAINING ROSE OIL AND CANNABIDIOL AND METHODS OF MAKING AND USING THE SAME | RXRG, CNR2, CUTA | NR3C2 3311/4885PGR 1003/4885NR3C1 2774/4885 |
| US-20210169759-A1 | TOPICAL COMPOSITIONS CONTAINING ROSE OIL AND CANNABIDIOL AND METHODS OF MAKING AND USING THE SAME | RXRG, CNR2, CUTA | NR3C2 3311/4885PGR 1003/4885NR3C1 2774/4885 |
| US-20210361591-A1 | COMPOSITIONS FOR TREATING ACNE AND DERMATOLOGICAL CONDITIONS | COQ8A, ATP5ME, AGK | NR3C2 4001/4885PGR 590/4885NR3C1 3071/4885 |
| US-20240130980-A1 | COMPOSITIONS FOR TREATING ACNE AND DERMATOLOGICAL CONDITIONS | COQ8A, ATP5ME, AGK | NR3C2 4001/4885PGR 590/4885NR3C1 3071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.