Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 8/20 | 0.74 |
| ▸ | AR | P10275 | 2/20 | 0.67 |
| ▸ | PGR | P06401 | 4/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | SHBG | P04278 | 2/20 | 0.51 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122186 | 0.88 | NR3C2 (0.79) | NR3C2ARPGRNR3C1HIF1A | |
| SCHEMBL14936105 | 0.85 | NR3C2 (1.00) | NR3C2ARPGRNR3C1HIF1A | |
| SCHEMBL3050557 | 0.85 | NR3C2 (1.00) | NR3C2ARPGRNR3C1HIF1A | |
| SCHEMBL180224 | 0.85 | NR3C2 (1.00) | NR3C2ARPGRNR3C1HIF1A | |
| SCHEMBL1028308 | 0.84 | NR3C2 (0.89) | NR3C2ARPGRNR3C1HIF1A | |
| SCHEMBL18506544 | 0.84 | NR3C2 (0.68) | NR3C2ARPGRNR3C1HIF1A | |
| SCHEMBL1030720 | 0.84 | PGR (0.84) | NR3C2ARPGRNR3C1HIF1A | |
| SCHEMBL23456329 | 0.83 | NR3C2 (0.70) | NR3C2ARPGRNR3C1HIF1A | |
| SCHEMBL1807731 | 0.83 | PGR (0.70) | NR3C2ARPGRNR3C1HIF1A | |
| SCHEMBL1807730 | 0.81 | PGR (0.68) | NR3C2ARPGRNR3C1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1588703-B1 | FATIGUE REDUCING AGENT | KANEKA CORP (JP) | 2016-04-20 | — | — | EP | disclosed |
| US-8946303-B2 | Fatigue reducing agent | KANEKA CORPORATION (JP) | 2015-02-03 | — | — | US | disclosed |
| EP-1481969-B1 | PIPERIDINE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-7425567-B2 | Piperidine derivative compounds and drugs containing the compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-09-16 | — | — | US | disclosed |
| US-7378428-B2 | Nitrogen-containing bicyclic compounds and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-05-27 | — | — | US | disclosed |
| US-20060165672-A1 | Fatigue reducing agent | KANEKA CORPORATION | 2006-07-27 | — | — | US | disclosed |
| EP-1588703-A1 | FATIGUE REDUCING AGENT | KANEKA CORPORATION (JP) | 2005-10-26 | — | — | EP | disclosed |
| US-20050222138-A1 | Nitrogen-containing bicyclic compounds and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-10-06 | — | — | US | disclosed |
| US-20050080107-A1 | Piperidine derivative compounds and drugs containing the compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-04-14 | — | — | US | disclosed |
| EP-1481969-A1 | PIPERIDINE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-12-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080107-A1 | Piperidine derivative compounds and drugs containing the compounds as the active ingredient | PDCD4, PDE4B, IRAK4 | NR3C2 3289/4885AR 2405/4885PGR 820/4885 |
| US-20060165672-A1 | Fatigue reducing agent | CPT1B, RECQL, NDUFB5 | NR3C2 4164/4885AR 4469/4885PGR 4543/4885 |
| US-20050222138-A1 | Nitrogen-containing bicyclic compounds and drugs containing the same as the active ingredient | PARK7, MMP8, CDK7 | NR3C2 94/4885AR 858/4885PGR 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.