Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21732663 | 0.83 | ADORA2A (0.44) | NOS3NOS1NOS2MEN1NPC1 | |
| SCHEMBL26671269 | 0.83 | PARP10 (0.43) | NOS3NOS1NOS2PARP1GSK3B | |
| SCHEMBL21722660 | 0.83 | ADORA2B (0.45) | NOS3NOS1NOS2PARP1PARP10 | |
| SCHEMBL23063304 | 0.83 | NOS3 (0.41) | NOS3NOS1NOS2GSK3B | |
| SCHEMBL29573616 | 0.83 | ADORA2B (0.45) | NOS3NOS1NOS2PARP1PARP10 | |
| SCHEMBL21732634 | 0.82 | ASIC3 (0.45) | NOS3NOS1NOS2NPC1RAB9A | |
| SCHEMBL21722744 | 0.82 | NOS3 (0.39) | NOS3NOS1NOS2PARP1NLRP3 | |
| SCHEMBL21732623 | 0.81 | NOS3 (0.38) | NOS3NOS1NOS2 | |
| SCHEMBL20636446 | 0.80 | MTOR (0.39) | NOS3NOS1NOS2NLRP3LNPEP | |
| SCHEMBL20634909 | 0.80 | NLRP3 (0.45) | NOS3NOS1NOS2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163412-A1 | NOVEL SULFONEUREA COMPOUNDS | INFLAZOME LIMITED (IE) | 2021-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163412-A1 | NOVEL SULFONEUREA COMPOUNDS | NLRP3, NLRP1, PYCARD | NOS3 582/4885NOS1 427/4885NOS2 886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.