SCHEMBL23480476

SCHEMBL23480476

COC(=O)[C@@H]1Cc2sccc2CN1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.49
ALDH1A1 P00352 2/20 0.48
MAPT P10636 2/20 0.48
KDM4E B2RXH2 2/20 0.48
HSD17B10 Q99714 2/20 0.48
CYP1A2 P05177 1/20 0.48
GAA P10253 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
CYP2C19 P33261 1/20 0.48
PNMT P11086 1/20 0.37
TSHR P16473 1/20 0.35
HTT P42858 1/20 0.35
BACE1 P56817 1/20 0.35
MMP9 P14780 2/20 0.33
MMP1 P03956 1/20 0.33
MMP3 P08254 1/20 0.33
ADAM17 P78536 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9789713 0.98 KMT2A (0.48) KMT2AALDH1A1MAPTKDM4EHSD17B10
Hydrochloric Acid SCHEMBL9789645 0.98 KMT2A (0.48) KMT2AALDH1A1MAPTKDM4EHSD17B10
Hydrochloric Acid SCHEMBL9789700 0.98 KMT2A (0.48) KMT2AALDH1A1MAPTKDM4EHSD17B10
SCHEMBL7979855 0.89 KMT2A (0.48) KMT2AALDH1A1MAPTKDM4EHSD17B10
SCHEMBL24184649 0.89 KMT2A (0.48) KMT2AALDH1A1MAPTKDM4EHSD17B10
Hydrochloric Acid SCHEMBL9789720 0.88 KMT2A (0.47) KMT2AALDH1A1MAPTKDM4EHSD17B10
SCHEMBL4465829 0.81 EGLN1 (0.48) KMT2AMAPTGAAPNMT
SCHEMBL11363930 0.81 EGLN1 (0.48) KMT2AMAPTGAAPNMT
Hydrochloric Acid SCHEMBL8383923 0.80 EGLN1 (0.47) KMT2AMAPTGAAPNMT
SCHEMBL1491696 0.79 KDM4E (0.56) KMT2AALDH1A1MAPTKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4678644-A1 SUBSTITUTED DIHYDROTHIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF Shanghai Yidi Biotechnology Co., Ltd. (CN) 2026-01-14 EP disclosed
US-20230190939-A1 ANTIBODY DRUG CONJUGATES COMPRISING TOXINS WITH POLAR GROUPS AND USES THEREOF INTOCELL, INC. (KR) 2023-06-22 US disclosed
US-20230190939-A1 ANTIBODY DRUG CONJUGATES COMPRISING TOXINS WITH POLAR GROUPS AND USES THEREOF INTOCELL, INC. (KR) 2023-06-22 US disclosed
US-20230039858-A1 COMPOSITIONS AND METHODS RELATED TO MOLECULAR CONJUGATION INTOCELL, INC. (KR) 2023-02-09 US disclosed
US-20220009946-A1 FUSED HETEROCYCLIC BENZODIAZEPINE DERIVATIVES AND USES THEREOF INTOCELL, INC. (KR) 2022-01-13 US disclosed
WO-2021111185-A1 COMPOSITIONS AND METHODS RELATED TO MOLECULAR CONJUGATION INTOCELL, INC. (KR) 2021-06-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190939-A1 ANTIBODY DRUG CONJUGATES COMPRISING TOXINS WITH POLAR GROUPS AND USES THEREOF CD47, ENPP2, CD2 KMT2A 3159/4885ALDH1A1 4468/4885MAPT 1430/4885
US-20220009946-A1 FUSED HETEROCYCLIC BENZODIAZEPINE DERIVATIVES AND USES THEREOF GABRB2, GABRB3, GABRB1 KMT2A 1898/4885ALDH1A1 1347/4885MAPT 1876/4885
US-20230039858-A1 COMPOSITIONS AND METHODS RELATED TO MOLECULAR CONJUGATION FCGR2A, FCGRT, FCGR3B KMT2A 832/4885ALDH1A1 200/4885MAPT 451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.