Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22609283 | 0.79 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL22609257 | 0.79 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL22609213 | 0.79 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL23453731 | 0.73 | RAPGEF4 (0.41) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22609268 | 0.70 | DHODH (0.43) | ALDH1A1LMNAHSD17B10ALOX15SMN1; SMN2 | |
| SCHEMBL22609335 | 0.68 | HTT (0.45) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL22609248 | 0.68 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL22609253 | 0.68 | ALDH1A1 (0.52) | KMT2AALDH1A1SMN1; SMN2ATMPOLB | |
| SCHEMBL27627423 | 0.68 | LMNA (0.46) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL23453717 | 0.68 | DHODH (0.41) | ALDH1A1CYP2C19HSD17B10ALOX15PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | ORFAN BIOTECH SL (ES) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | PNPO, XDH, GLS | PTGS2 553/4885ALOX5 69/4885PTGS1 242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.