Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4230820 | 0.95 | MAPK1 (0.56) | MAPK1ALDH1A1GCGRMAPK14PTPRC | |
| SCHEMBL29687904 | 0.88 | ALDH1A1 (0.70) | MAPK1ALDH1A1MAOAMAOBHPGD | |
| SCHEMBL9762542 | 0.88 | ALDH1A1 (0.70) | MAPK1ALDH1A1MAOAMAOBHPGD | |
| SCHEMBL31232605 | 0.86 | ALDH1A1 (0.47) | MAPK1ALDH1A1GCGRMAPK14PTPRC | |
| SCHEMBL29363731 | 0.86 | ALDH1A1 (0.47) | MAPK1ALDH1A1GCGRMAPK14PTPRC | |
| SCHEMBL21662218 | 0.84 | CYP2A6 (0.54) | MAPK1ALDH1A1HSD11B1PDK2MAOB | |
| SCHEMBL3561173 | 0.83 | ALDH1A1 (0.58) | MAPK1ALDH1A1PDK2MAOBTSHR | |
| SCHEMBL21037629 | 0.79 | ALDH1A1 (0.73) | MAPK1ALDH1A1MAOAMAOBHPGD | |
| SCHEMBL21202807 | 0.79 | ALDH1A1 (0.73) | MAPK1ALDH1A1MAOAMAOBHPGD | |
| SCHEMBL554192 | 0.79 | ALDH1A1 (0.65) | MAPK1ALDH1A1GCGRMAPK14HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230056324-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| WO-2021110720-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2021-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230056324-A1 | METAL COMPLEXES | MCU, IMMT, SOD1 | MAPK1 4720/4885ALDH1A1 1713/4885GCGR 4090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.