SCHEMBL554192

SCHEMBL554192

Clc1ccc(-c2ccccc2Br)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.65
MAPK1 P28482 2/20 0.65
PTGS2 P35354 2/20 0.52
PTGS1 P23219 1/20 0.52
CYP1A2 P05177 3/20 0.50
GCGR P47871 1/20 0.47
MAPK14 Q16539 1/20 0.47
TSHR P16473 5/20 0.44
HPGD P15428 3/20 0.44
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
CYP2A6 P11509 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NPC1 O15118 4/20 0.40
RAB9A P51151 4/20 0.40
TP53 P04637 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25672847 0.98 ALDH1A1 (0.62) ALDH1A1MAPK1PTGS2PTGS1CYP1A2
SCHEMBL30758907 0.91 ALDH1A1 (0.54) ALDH1A1MAPK1PTGS2PTGS1CYP1A2
SCHEMBL12489603 0.87 ALDH1A1 (0.83) ALDH1A1MAPK1TSHRHPGDTDP1
SCHEMBL23533675 0.84 MAPK1 (0.52) ALDH1A1MAPK1PTGS2PTGS1CYP1A2
SCHEMBL9862848 0.82 CYP1A2 (0.63) ALDH1A1PTGS2PTGS1CYP1A2TSHR
SCHEMBL673353 0.80 MAPK1 (0.71) ALDH1A1MAPK1TSHRHPGDSLC6A3
SCHEMBL3778039 0.80 ALDH1A1 (0.90) ALDH1A1MAPK1PTGS2CYP1A2TSHR
SCHEMBL30121160 0.80 ALDH1A1 (0.90) ALDH1A1MAPK1PTGS2CYP1A2TSHR
SCHEMBL30523573 0.80 ALDH1A1 (0.52) ALDH1A1MAPK1PTGS2PTGS1CYP1A2
SCHEMBL18133372 0.80 CYP2A6 (0.52) ALDH1A1MAPK1PTGS2PTGS1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 341 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119361834-A Electrolyte and battery and electricity utilization device containing same 浙江大学 2025-01-24 CN claimed
CN-114230433-B Synthesis method of 2-bromo-4 '-chloro-1, 1' -biphenyl 郑州海阔光电材料有限公司 2023-10-20 CN claimed
CN-116768785-A Synthesis method of spirofluorene-containing indole derivative structure 西安欧得光电材料有限公司 2023-09-19 CN claimed
CN-114230433-A Synthetic method of 2-bromo-4 '-chloro-1, 1' -biphenyl 郑州海阔光电材料有限公司 2022-03-25 CN claimed
CN-122094955-A Compound, light-emitting device, display device, electronic apparatus, and lighting device 2026-05-26 CN disclosed
US-12630496-B2 Organic compound, light-emitting device, light-emitting apparatus, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2026-05-19 US disclosed
US-20260092057-A1 BCL-XL/BCL-2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-02 US disclosed
US-12552809-B2 Compound for organic electric element, organic electric element comprising the same, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2026-02-17 US disclosed
US-20260035339-A1 TETRAHYDRONAPHTHALENE DERIVATIVE ATRANSEN PHARMA LTD (JP) 2026-02-05 US disclosed
US-20260040760-A1 Hole-Transport Layer Material, Electron-Blocking Layer Material, Electron-Transport Layer Material, Hole-Blocking Layer Material, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, And Lighting Device SEMICONDUCTOR ENERGY LAB (JP) 2026-02-05 US disclosed
US-12527215-B2 Compound for organic electrical element, organic electrical element using same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2026-01-13 US disclosed
US-20250359423-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS THEREOF SHAANXI LIGHTE OPTOELECTRONICS MAT CO LTD (CN) 2025-11-20 US disclosed
WO-2005049593-A2 N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS ABBOTT LABORATORIES (US) 2005-06-02 WO disclosed
US-20040158074-A1 Substituted biphenyl compounds for the treatment of inflammation G.D. SEARLE & CO. 2004-08-12 US disclosed
US-6677488-B2 AS AN EXAMPLE, 4-(4,5-DIFLUORO-2-(3-CHLORO-4-FLUOROPHENYL) PHENYLBENZENESULFONAMIDE; ANTIARTHRITIC AGENTS; ANTIPYRETICS; ANALGESICS; PROSTAGLANDIN INHIBITORS; SIDE EFFECT REDUCTION G.D. SEARLE & CO. 2004-01-13 US disclosed
US-20020169206-A1 Substituted biphenyl compounds for the treatment of inflammation G.D. SEARLE & CO. (US) 2002-11-14 US disclosed
EP-0794942-B1 SUBSTITUTED BIPHENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION SEARLE & CO (US) 2000-05-31 EP disclosed
US-5739166-A ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT G.D. SEARLE & CO. (US) 1998-04-14 US disclosed
EP-0794942-A1 SUBSTITUTED BIPHENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1997-09-17 EP disclosed
WO-1996016934-A1 SUBSTITUTED BIPHENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1996-06-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020169206-A1 Substituted biphenyl compounds for the treatment of inflammation AHR, ARNT, GPBAR1 ALDH1A1 241/4885MAPK1 1864/4885PTGS2 379/4885
US-20260040760-A1 Hole-Transport Layer Material, Electron-Blocking Layer Material, Electron-Transport Layer Material, Hole-Blocking Layer Material, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, And Lighting Device CTNNB1, AXIN2, SLC9A2 ALDH1A1 2982/4885MAPK1 1033/4885PTGS2 3393/4885
US-20040158074-A1 Substituted biphenyl compounds for the treatment of inflammation AHR, ARNT, GPBAR1 ALDH1A1 241/4885MAPK1 1864/4885PTGS2 379/4885
US-20260092057-A1 BCL-XL/BCL-2 DEGRADERS AND USES THEREOF BCL2L2, BCL2A1, BCL2L1 ALDH1A1 1304/4885MAPK1 2564/4885PTGS2 178/4885
US-20250359423-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS THEREOF PIEZO1, SLCO4C1, POU2F1 ALDH1A1 580/4885MAPK1 1346/4885PTGS2 2823/4885
US-20260035339-A1 TETRAHYDRONAPHTHALENE DERIVATIVE LATS1, LATS2, BCAT1 ALDH1A1 1267/4885MAPK1 152/4885PTGS2 3642/4885
US-12552809-B2 Compound for organic electric element, organic electric element comprising the same, and electronic device thereof KCNE1, KCNN4, RER1 ALDH1A1 1374/4885MAPK1 659/4885PTGS2 3341/4885
US-12630496-B2 Organic compound, light-emitting device, light-emitting apparatus, electronic device, and lighting device CRY1, NR1I2, GNA11 ALDH1A1 66/4885MAPK1 1472/4885PTGS2 2858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.