Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891044 | 0.68 | HMBS (0.39) | HDAC4HDAC2HDAC8 | |
| SCHEMBL891324 | 0.65 | USP2 (0.35) | HDAC4HDAC2HDAC8 | |
| SCHEMBL25618771 | 0.65 | USP2 (0.35) | HDAC4HDAC2HDAC8 | |
| SCHEMBL11686432 | 0.59 | ALDH1A1 (0.46) | HDAC4HDAC2HDAC8LMNA | |
| SCHEMBL19365913 | 0.59 | HDAC4 (0.46) | HDAC4HDAC2HDAC8LMNA | |
| SCHEMBL20965373 | 0.58 | DAO (0.46) | HDAC4HDAC2HDAC8 | |
| SCHEMBL28116328 | 0.57 | ALDH1A1 (0.39) | — | |
| SCHEMBL18400785 | 0.56 | MEN1 (0.40) | LMNA | |
| SCHEMBL12552556 | 0.56 | ALDH1A1 (0.50) | HDAC4HDAC2HDAC8 | |
| SCHEMBL2758514 | 0.55 | ALDH1A1 (0.39) | HDAC4HDAC2HDAC8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171475-A1 | COMPOUNDS | UCL BUSINESS LTD (GB) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171475-A1 | COMPOUNDS | GOT2, GOT1, OAT | HDAC4 1455/4885HDAC2 1618/4885HDAC8 1247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.