Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 12/20 | 0.55 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867861 | 0.72 | GABRA2 (0.65) | NOTUM | |
| SCHEMBL21776985 | 0.71 | NOTUM (1.00) | NOTUM | |
| SCHEMBL22584705 | 0.70 | AR (0.68) | NOTUMARKCNH2CA12CA1 | |
| SCHEMBL23488361 | 0.69 | NOTUM (1.00) | NOTUM | |
| SCHEMBL29479281 | 0.67 | NOTUM (0.53) | NOTUMKCNH2CA12CA1CA2 | |
| SCHEMBL24958858 | 0.67 | NOTUM (0.52) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL31636683 | 0.66 | NOTUM (0.57) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL28904479 | 0.64 | CA12 (0.51) | NOTUMKCNH2CA12CA1CA2 | |
| SCHEMBL2886167 | 0.63 | P2RX7 (0.52) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL25946907 | 0.62 | KAT7 (0.41) | NOTUMARRXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171475-A1 | COMPOUNDS | UCL BUSINESS LTD (GB) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171475-A1 | COMPOUNDS | GOT2, GOT1, OAT | NOTUM 5/4885AR 3945/4885KCNH2 4604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.