Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | APP | P05067 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23488400 | 0.87 | SMN1; SMN2 (0.68) | HCAR3SMN1; SMN2CYP2C19RAB9ANPC1 | |
| SCHEMBL2664544 | 0.86 | HCAR3 (1.00) | HCAR3SMN1; SMN2RAB9ANPC1DEGS1 | |
| SCHEMBL22983005 | 0.85 | ALDH1A1 (0.68) | HCAR3SMN1; SMN2ALDH1A1CYP2C19RAB9A | |
| SCHEMBL31672283 | 0.83 | DEGS1 (0.68) | SMN1; SMN2GAACYP2C19RAB9ANPC1 | |
| SCHEMBL17040257 | 0.83 | DEGS1 (0.68) | SMN1; SMN2GAACYP2C19RAB9ANPC1 | |
| SCHEMBL11887841 | 0.82 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1CYP2C19RAB9ANPC1 | |
| SCHEMBL15291342 | 0.82 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1GAACYP2C19RAB9A | |
| SCHEMBL6646471 | 0.80 | RAB9A (0.70) | SMN1; SMN2RAB9ANPC1LMNAHIF1A | |
| SCHEMBL31414959 | 0.80 | RAB9A (0.70) | SMN1; SMN2RAB9ANPC1LMNAHIF1A | |
| SCHEMBL7329481 | 0.80 | ROCK2 (0.73) | HCAR3SMN1; SMN2ALDH1A1APPGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | SANOFI (FR) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | GPR119, SLC2A8, SLC2A4 | HCAR3 447/4885SMN1; SMN2 3945/4885ALDH1A1 1627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.