SCHEMBL23488690

SCHEMBL23488690

CC1O[C@H](CO)[C@@H](O)[C@H](OC(=O)c2ccc(OCc3ccccc3)cc2)[C@H]1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 5/20 0.55
LGALS9 O00182 4/20 0.55
LGALS1 P09382 4/20 0.55
LGALS7; LGALS7B P47929 3/20 0.55
LGALS8 O00214 4/20 0.50
MAOB P27338 1/20 0.47
NR4A1 P22736 1/20 0.46
NR4A2 P43354 1/20 0.46
NR4A3 Q92570 1/20 0.46
SELP P16109 5/20 0.45
PARP10 Q53GL7 1/20 0.44
SRD5A2 P31213 1/20 0.43
SELE P16581 1/20 0.43
HIF1A Q16665 1/20 0.43
PLA2G4B P0C869 1/20 0.42
LGALS4 P56470 1/20 0.42
CHRNB2 P17787 1/20 0.41
CHRNA5 P30532 1/20 0.41
CHRNA7 P36544 1/20 0.41
CHRNA4 P43681 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23488416 0.92 LGALS9 (0.49) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL23488692 0.92 MAOB (0.47) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL23488513 0.88 LGALS8 (0.64) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL22490855 0.85 LGALS3 (0.50) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL22490926 0.85 LGALS3 (0.50) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL22490919 0.85 LGALS3 (0.50) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL23488412 0.83 LGALS8 (0.53) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL23488143 0.83 LGALS8 (0.53) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL23488417 0.83 LGALS8 (0.53) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL23488160 0.81 LGALS3 (0.48) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 LGALS3 156/4885LGALS9 106/4885LGALS1 50/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.