Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20434505 | 0.86 | TPSAB1 (0.46) | PRSS1TPSAB1ALDH1A1CYP1A2NPC1 | |
| SCHEMBL26502414 | 0.86 | MEN1 (0.49) | PRSS1TPSAB1NPC1RAB9A | |
| SCHEMBL13687217 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HPGDMAPTCHRNB2CHRNB4 | |
| SCHEMBL24761197 | 0.82 | PRSS1 (0.43) | PRSS1TPSAB1ALDH1A1NPC1HPGD | |
| SCHEMBL24062673 | 0.82 | PRSS1 (0.47) | PRSS1TPSAB1MMP2MMP12P2RX4 | |
| SCHEMBL11131589 | 0.80 | MMP2 (0.49) | PRSS1TPSAB1MMP2MMP12P2RX4 | |
| SCHEMBL24591903 | 0.79 | MMP2 (0.47) | PRSS1TPSAB1MMP2MMP12P2RX4 | |
| SCHEMBL15601806 | 0.79 | PRSS1 (0.51) | PRSS1TPSAB1MMP2MMP12P2RX4 | |
| SCHEMBL25962335 | 0.79 | PRSS1 (0.42) | PRSS1TPSAB1MMP2MMP12P2RX4 | |
| SCHEMBL21348175 | 0.78 | PRSS1 (0.44) | PRSS1TPSAB1MMP2MMP12P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381323-A1 | RELEASABLE CONJUGATES | FISH & RICHARDSON PC | 2023-11-30 | — | — | US | disclosed |
| US-11786599-B2 | Releasable conjugates | QUIAPEG PHARMACEUTICALS AB (SE) | 2023-10-17 | — | — | US | disclosed |
| US-11357828-B2 | Releasable GLP-1 conjugates | QUIAPEG PHARMACEUTICALS AB (SE) | 2022-06-14 | — | — | US | disclosed |
| US-20220118055-A1 | RELEASABLE GLP-1 CONJUGATES | FISH & RICHARDSON PC | 2022-04-21 | — | — | US | disclosed |
| US-20210170045-A1 | RELEASABLE ANTIBODY CONJUGATES | FISH & RICHARDSON PC | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210170045-A1 | RELEASABLE ANTIBODY CONJUGATES | BCR, CD47, RNASE1 | PRSS1 2946/4885TPSAB1 1184/4885MMP2 342/4885 |
| US-20230381323-A1 | RELEASABLE CONJUGATES | GUSB, ABCB11, UGT2B7 | PRSS1 1498/4885TPSAB1 240/4885MMP2 257/4885 |
| US-11357828-B2 | Releasable GLP-1 conjugates | GLP1R, GIPR, IAPP | PRSS1 1267/4885TPSAB1 424/4885MMP2 1462/4885 |
| US-11786599-B2 | Releasable conjugates | GUSB, ABCB11, UGT2B7 | PRSS1 1498/4885TPSAB1 240/4885MMP2 257/4885 |
| US-20220118055-A1 | RELEASABLE GLP-1 CONJUGATES | GLP1R, GIPR, IAPP | PRSS1 1267/4885TPSAB1 424/4885MMP2 1462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.