Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 4/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15022121 | 0.94 | FFAR3 (0.36) | CA4FFAR3HDAC3HDAC1HDAC2 | |
| Lithium Ion SCHEMBL18321792 | 0.94 | FFAR3 (0.36) | CA4FFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL4777919 | 0.94 | FFAR3 (0.41) | CA4FFAR3HDAC3HDAC1HDAC2 | |
| Silver SCHEMBL17797184 | 0.94 | FFAR3 (0.36) | CA4FFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL4957927 | 0.94 | FFAR3 (0.36) | CA4FFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL6818429 | 0.94 | FFAR3 (0.36) | CA4FFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL11649902 | 0.91 | FFAR3 (0.35) | CA4FFAR3HDAC3HDAC1HDAC2 | |
| Tetramethylammonium Ion SCHEMBL2348519 | 0.88 | BBOX1 (0.38) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Potassium Ion SCHEMBL28681486 | 0.86 | CYP4F2 (0.32) | CA4FFAR3HDAC3HDAC1HDAC2 | |
| Tetrylammonium SCHEMBL2351305 | 0.84 | TSHR (0.40) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110546-B1 | METHOD FOR MAKING A POLYISOCYANURATE/POLYURETHANE FOAM | EVONIK OPERATIONS GMBH (DE) | 2022-03-30 | — | — | EP | claimed |
| CN-107922564-B | Trimerization catalysts from sterically hindered salts and tertiary amines having isocyanate-reactive groups | 赢创运营有限公司 | 2021-10-19 | — | — | CN | claimed |
| EP-3310827-B1 | TRIMERIZATION CATALYSTS FROM STERICALLY HINDERED SALTS AND TERTIARY AMINES HAVING ISOCYANATE REACTIVE GROUPS | EVONIK OPERATIONS GMBH (DE) | 2021-01-06 | — | — | EP | claimed |
| US-10759892-B2 | Trimerization catalysts from sterically hindered salts and tertiary amines having isocyanate reactive groups | EVONIK OPERATIONS GMBH (DE) | 2020-09-01 | — | — | US | claimed |
| US-10125234-B2 | Catalyst compositions and methods for making foam | EVONIK DEGUSSA GMBH (DE) | 2018-11-13 | — | — | US | claimed |
| US-20180179318-A1 | TRIMERIZATION CATALYSTS FROM STERICALLY HINDERED SALTS AND TERTIARY AMINES HAVING ISOCYANATE REACTIVE GROUPS | EVONIK OPERATIONS GMBH (DE) | 2018-06-28 | — | — | US | claimed |
| EP-3310827-A1 | TRIMERIZATION CATALYSTS FROM STERICALLY HINDERED SALTS AND TERTIARY AMINES HAVING ISOCYANATE REACTIVE GROUPS | Evonik Degussa GmbH (DE) | 2018-04-25 | — | — | EP | claimed |
| US-9890236-B2 | Trimerization catalysts from sterically hindered salts | EVONIK DEGUSSA GMBH (DE) | 2018-02-13 | — | — | US | claimed |
| EP-3110546-A1 | CATALYST COMPOSITIONS AND METHODS FOR MAKING FOAM | Air Products and Chemicals, Inc. (US) | 2017-01-04 | — | — | EP | claimed |
| WO-2016201675-A1 | TRIMERIZATION CATALYSTS FROM STERICALLY HINDERED SALTS AND TERTIARY AMINES HAVING ISOCYANATE REACTIVE GROUPS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2016-12-22 | — | — | WO | claimed |
| WO-2015130939-A1 | CATALYST COMPOSITIONS AND METHODS FOR MAKING FOAM | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2015-09-03 | — | — | WO | claimed |
| US-20150240023-A1 | Catalyst Compositions and Methods for Making Foam | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2015-08-27 | — | — | US | claimed |
| US-20130341562-A1 | TRIMERIZATION CATALYSTS FROM STERICALLY HINDERED SALTS | AIR PRODUCTS AND CHEMICALS INC. (US) | 2013-12-26 | — | — | US | claimed |
| US-8530534-B2 | Trimerization catalysts from sterically hindered salts | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2013-09-10 | — | — | US | claimed |
| EP-1852448-B1 | New trimerization catalysts from sterically hindered salts | AIR PROD & CHEM (US) | 2011-08-31 | — | — | EP | claimed |
| US-20070259983-A1 | Trimerization catalysts from sterically hindered salts | EVONIK OPERATIONS GMBH (DE) | 2007-11-08 | — | — | US | claimed |
| EP-1852448-A2 | New trimerization catalysts from sterically hindered salts | Air Products and Chemicals, Inc. (US) | 2007-11-07 | — | — | EP | claimed |
| US-20260139090-A1 | POLYURETHANE INSULATION FOAM COMPOSITION COMPRISING A STABILIZING COMPOUND | HUNTSMAN INT LLC (US) | 2026-05-21 | — | — | US | disclosed |
| US-20070259983-A1 | Trimerization catalysts from sterically hindered salts | EVONIK OPERATIONS GMBH (DE) | 2007-11-08 | — | — | US | disclosed |
| EP-1852448-A2 | New trimerization catalysts from sterically hindered salts | Air Products and Chemicals, Inc. (US) | 2007-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260139090-A1 | POLYURETHANE INSULATION FOAM COMPOSITION COMPRISING A STABILIZING COMPOUND | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HCFC1, RFC5 | CA4 1101/4885FFAR3 35/4885HDAC3 1462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.