Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2350335 | 0.82 | LMNA (0.42) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL15257108 | 0.80 | — | — | |
| SCHEMBL3680811 | 0.73 | MMP2 (0.38) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL27446364 | 0.71 | PNMT (0.37) | ALDH1A1LMNAGAAPAX8MCL1 | |
| SCHEMBL16174000 | 0.70 | ESR2 (0.31) | — | |
| SCHEMBL16174056 | 0.69 | ACHE (0.40) | ALDH1A1 | |
| SCHEMBL28311778 | 0.68 | MEN1 (0.32) | MEN1KMT2AALDH1A1 | |
| SCHEMBL20240642 | 0.67 | MMP2 (0.39) | ALDH1A1LMNAGAAPAX8MCL1 | |
| SCHEMBL19936870 | 0.65 | ALDH1A1 (0.34) | ALDH1A1LMNAGAAPAX8MCL1 | |
| SCHEMBL8873990 | 0.65 | MMP2 (0.47) | MEN1KMT2AALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461403-B2 | Carbon nanohoops and methods of making | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-06-11 | — | — | US | disclosed |
| US-20110166390-A1 | CARBON NANOHOOPS AND METHODS OF MAKING | LAWRENCE BERKELEY NATIONAL LABORATORY (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166390-A1 | CARBON NANOHOOPS AND METHODS OF MAKING | CYCS, CDC42, NCDN | MEN1 1467/4885KMT2A 3516/4885HTT 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.