Phenazine

Phenazine

SCHEMBL23522712

O=S(O)(O)=S.c1ccc2nc3ccccc3nc2c1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.58
ALDH1A1 P00352 7/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
NQO2 P16083 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
KMT2A Q03164 3/20 0.43
RAB9A P51151 3/20 0.43
GAA P10253 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
NPC1 O15118 3/20 0.42
POLB P06746 2/20 0.42
MEN1 O00255 2/20 0.42
USP2 O75604 1/20 0.42
CACNA1B Q00975 1/20 0.42
APBA1 Q02410 1/20 0.42
HPGD P15428 3/20 0.42
HSD17B10 Q99714 2/20 0.42
KDM4E B2RXH2 2/20 0.42
GLA P06280 1/20 0.42
ACHE P22303 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenazine SCHEMBL2923781 0.89 MAPT (0.65) MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1
Phenazine SCHEMBL8564741 0.89 MAPT (0.65) MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1
Phenazine SCHEMBL28835271 0.86 MAPT (0.61) MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1
Phenazine SCHEMBL1750964 0.84 MAPT (0.58) MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1
Phenazine SCHEMBL23522711 0.84 MAPT (0.58) MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1
Phenazine SCHEMBL28366239 0.82 MAPT (0.55) MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1
Phenazine SCHEMBL22631548 0.82 MAPT (0.55) MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1
Phenazine SCHEMBL28658053 0.82 MAPT (0.55) MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1
Phenazine SCHEMBL94396 0.78 MAPT (0.50) MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1
Phenazine SCHEMBL2873102 0.78 MAPT (0.50) MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492451-B2 Metal-binding protein and use thereof THE PENN STATE RESEARCH FOUNDATION (US) 2025-12-09 US disclosed
US-20210189521-A1 METAL-BINDING PROTEIN AND USE THEREOF THE PENN STATE RESEARCH FOUNDATION 2021-06-24 US disclosed
CN-112930190-A Metal binding proteins and uses thereof 宾州研究基金会 2021-06-08 CN disclosed