Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phenazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | NQO2 | P16083 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenazine SCHEMBL8564741 | 1.00 | MAPT (0.65) | MAPTALDH1A1NQO2SMN1; SMN2L3MBTL1 | |
| Phenazine SCHEMBL28835271 | 0.97 | MAPT (0.61) | MAPTALDH1A1NQO2SMN1; SMN2L3MBTL1 | |
| Phenazine SCHEMBL23522712 | 0.89 | MAPT (0.58) | MAPTALDH1A1NQO2SMN1; SMN2L3MBTL1 | |
| Phenazine SCHEMBL1750964 | 0.89 | MAPT (0.58) | MAPTALDH1A1NQO2SMN1; SMN2L3MBTL1 | |
| Phenazine SCHEMBL23522711 | 0.89 | MAPT (0.58) | MAPTALDH1A1NQO2SMN1; SMN2L3MBTL1 | |
| Phenazine SCHEMBL28366239 | 0.87 | MAPT (0.55) | MAPTALDH1A1NQO2SMN1; SMN2L3MBTL1 | |
| Phenazine SCHEMBL22631548 | 0.87 | MAPT (0.55) | MAPTALDH1A1NQO2SMN1; SMN2L3MBTL1 | |
| Phenazine SCHEMBL28658053 | 0.87 | MAPT (0.55) | MAPTALDH1A1NQO2SMN1; SMN2L3MBTL1 | |
| Acridine SCHEMBL10831095 | 0.85 | ALDH1A1 (0.71) | MAPTALDH1A1NQO2SMN1; SMN2L3MBTL1 | |
| Acridine SCHEMBL11600717 | 0.85 | ALDH1A1 (0.71) | MAPTALDH1A1NQO2SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180180587-A1 | PAPER MICROFLUIDIC DEVICES FOR DETECTION OF IMPROVISED EXPLOSIVES | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2018-06-28 | — | — | US | claimed |
| US-9891207-B2 | Paper microfluidic devices for detection of improvised explosives | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2018-02-13 | — | — | US | claimed |
| US-20160139102-A1 | PAPER MICROFLUIDIC DEVICES FOR DETECTION OF IMPROVISED EXPLOSIVES | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2016-05-19 | — | — | US | claimed |
| CN-114096563-B | Antibodies that specifically bind to B7-H3 and uses thereof | Y生物股份有限公司 | 2025-04-18 | — | — | CN | disclosed |
| WO-2024249566-A1 | NOVEL BIOBATTERY AND ITS USE FOR POWERING APPLICATIONS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2024-12-05 | — | — | WO | disclosed |
| CN-113993897-B | Anti-TIE 2 antibodies and uses thereof | 药物抗体公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-116670273-A | Method for measuring in a biosensor | 北卡罗来纳大学教堂山分校 | 2023-08-29 | — | — | CN | disclosed |
| CN-116236481-A | Application of Dp44mT in preparation of anti-candida albicans drugs | 上海市同济医院 | 2023-06-09 | — | — | CN | disclosed |
| EP-4018791-A1 | METHOD OF PREPARING A HIGH DENSITY INTERCONNECT PRINTED CIRCUIT BOARD INCLUDING MICROVIAS FILLED WITH COPPER | Atotech Deutschland GmbH & Co. KG (DE) | 2022-06-29 | — | — | EP | disclosed |
| CN-114466658-A | Orally delivered therapeutic compositions and uses thereof | 沈海发 | 2022-05-10 | — | — | CN | disclosed |
| WO-2022062380-A1 | TIBETAN GANODERMA LUCIDUM POLYSACCHARIDE GLP-1 WITH ANTIOXIDANT EFFECT, PREPARATION METHOD AND USE | 广东省微生物研究所（广东省微生物分析检测中心） | 2022-03-31 | — | — | WO | disclosed |
| US-20030178998-A1 | Enzyme electrode | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2003-09-25 | — | — | US | disclosed |
| EP-1321763-A1 | ENZYME ELECTRODE | Asahi Kasei Kabushiki Kaisha (JP) | 2003-06-25 | — | — | EP | disclosed |
| CN-1416354-A | Vascular endothelial growth factor 2 | HUMAN GENOME SCIENCES INC (US) | 2003-05-07 | — | — | CN | disclosed |
| US-5909114-A | Coulometric analysis method and a device therefor | NAKANO VINEGAR CO., LTD. (JP) | 1999-06-01 | — | — | US | disclosed |
| US-5726565-A | FOR QUANTITATIVE DETERMINATION OF A SAMPLE SUBSTANCE | NAKANO VINEGAR CO., LTD. (JP) | 1998-03-10 | — | — | US | disclosed |
| US-5334508-A | A mixture reagent consisting of an oxidoreductase enzyme, an aromatic nitroso or a oxime compound and a couplers; free of reducing catalysts, side-effect reduction | BOEHRINGER MANNHEIM GMBH (DE) | 1994-08-02 | — | — | US | disclosed |
| EP-0600607-A2 | Coulometric analysis method and a device therefor | NAKANO VINEGAR CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |
| US-5206147-A | COLORIMETRIC ASSAY BY ENZYMATIC OXIDATION IN THE PRESENCE OF AN AROMATIC NITROSO OR OXIME COMPOUND | BOEHRINGER MANNHEIM GMBH (DE) | 1993-04-27 | — | — | US | disclosed |
| US-4788141-A | BLOOD; HEPATITIS TESTING | MARUHO CO., LTD. (JP) | 1988-11-29 | — | — | US | disclosed |