Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenazine SCHEMBL8564741 | 0.87 | MAPT (0.65) | MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1 | |
| Phenazine SCHEMBL2923781 | 0.87 | MAPT (0.65) | MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1 | |
| Phenazine SCHEMBL28658053 | 0.85 | MAPT (0.55) | MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1 | |
| Phenazine SCHEMBL28835271 | 0.84 | MAPT (0.61) | MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1 | |
| Phenazine SCHEMBL23522711 | 0.82 | MAPT (0.58) | MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1 | |
| Phenazine SCHEMBL1750964 | 0.82 | MAPT (0.58) | MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1 | |
| Phenazine SCHEMBL23522712 | 0.82 | MAPT (0.58) | MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1 | |
| Phenazine SCHEMBL22631548 | 0.80 | MAPT (0.55) | MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1 | |
| Quinoline SCHEMBL336070 | 0.79 | ALDH1A1 (0.65) | MAPTALDH1A1SMN1; SMN2L3MBTL1POLB | |
| Phenazine SCHEMBL94396 | 0.76 | MAPT (0.50) | MAPTALDH1A1SMN1; SMN2NQO2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107870190-B | Genetic biochemical locus marker of cerebral ischemia inbred-line meriones unguiculatus and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-02-07 | — | — | CN | disclosed |