Phenazine

Phenazine

SCHEMBL94396

COS(=O)(=O)O.c1ccc2nc3ccccc3nc2c1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3

The experimentally established mechanism targets of Phenazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.50
NQO2 P16083 7/20 0.48
ALDH1A1 P00352 6/20 0.45
POLB P06746 4/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MEN1 O00255 2/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
KMT2A Q03164 2/20 0.45
KDM4E B2RXH2 1/20 0.45
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenazine SCHEMBL2873102 1.00 MAPT (0.50) MAPTNQO2ALDH1A1POLBSMN1; SMN2
Phenazine SCHEMBL10876543 1.00 MAPT (0.50) MAPTNQO2ALDH1A1POLBSMN1; SMN2
Acridine SCHEMBL2823221 0.88 ALDH1A1 (0.58) MAPTNQO2ALDH1A1POLBSMN1; SMN2
Phenazine SCHEMBL22631548 0.86 MAPT (0.55) MAPTNQO2ALDH1A1POLBSMN1; SMN2
Phenazine SCHEMBL7095188 0.85 MAPT (0.44) MAPTNQO2ALDH1A1POLBSMN1; SMN2
SCHEMBL9602629 0.84 MEN1 (0.46) MAPTNQO2ALDH1A1POLBSMN1; SMN2
SCHEMBL997540 0.84 NQO2 (0.49) MAPTNQO2ALDH1A1POLBSMN1; SMN2
SCHEMBL31031113 0.84 NQO2 (0.49) MAPTNQO2ALDH1A1POLBSMN1; SMN2
SCHEMBL3129032 0.84 NQO2 (0.49) MAPTNQO2ALDH1A1POLBSMN1; SMN2
SCHEMBL4063489 0.84 KMT2A (0.47) MAPTNQO2ALDH1A1POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10126 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122038528-A LDHA enzyme activity detection method based on MTS color development system 深圳大学 2026-05-15 CN claimed
US-12606858-B2 Methods, kits and devices for measuring extracellular pyridine nucleotide Charité—Universitäetsmedizin Berlin (DE) 2026-04-21 US claimed
EP-4720268-A1 COPPER DEHYDROGENASES ENGINEERED FROM MULTICOPPER OXIDASES AND THEIR BIOELECTROCHEMICAL APPLICATIONS The University of North Carolina at Chapel Hill (US) 2026-04-08 EP claimed
US-20260078142-A1 FULLY-CONTINUOUS SYNTHESIS METHOD OF CYPROTERONE ACETATE UNIV FUDAN (CN) 2026-03-19 US claimed
US-12453495-B2 Hormone electrochemical biosensor TRUSTEES OF BOSTON UNIVERSITY (US) 2025-10-28 US claimed
EP-4555324-A1 DETERMINATION OF HEMATOCRIT IDEXX Laboratories, Inc. (US) 2025-05-21 EP claimed
WO-2025095525-A1 ELECTRODE FOR ELECTROCHEMICAL SENSOR, ELECTROCHEMICAL SENSOR COMPRISING SAME, AND METHOD FOR MANUFACTURING ELECTROCHEMICAL SENSOR 동우 화인켐 주식회사 2025-05-08 WO claimed
CN-119931969-A Dehydrogenase and method for synthesizing 11 alpha-OH-ADD 湖北共同甾体药物研究院有限公司 2025-05-06 CN claimed
CN-119799663-A N-oxygenase double-site mutant and application thereof in synthesis of azomycin 中国科学院青岛生物能源与过程研究所 2025-04-11 CN claimed
CN-119685276-A Exemestane dehydrogenase, gene, strain and exemestane preparation method 湖南新合新生物医药有限公司 2025-03-25 CN claimed
US-4345027-A Fluorometric method of quantitative cell mutagenesis THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1982-08-17 US claimed
US-4266022-A MEDICAL DIAGNOSTIC AID FOR LEUKEMIA OR CANCER KOMMANDITGESELLSCHAFT SCHWARZHAUPT (DE) 1981-05-05 US claimed
US-4245041-A Triglycerides assay and reagents therefor AMERICAN MONITOR CORPORATION (US) 1981-01-13 US claimed
EP-0016129-A1 SEMI-QUANTITATIVE ASSAY OF METABOLIC ACIDS OWEN, Oliver E. (US) 1980-10-01 EP claimed
WO-1980000259-A1 SEMI-QUANTITATIVE ASSAY OF METABOLIC ACIDS OWEN O 1980-02-21 WO claimed
US-4157279-A Process for the determination of at least one of the isoenzymes of lactatedehydrogenase KOMMANDITGESELLSCHAFT SCHWARZHAUPT (DE) 1979-06-05 US claimed
US-4152116-A COLORIMETRIC, DECYCLIZATION, OXIDATION BOEHRINGER MANNHEIM GMBH (DE) 1979-05-01 US claimed
US-4042462-A OXIDATION OF NADPH MONSANTO COMPANY (US) 1977-08-16 US claimed
US-4038146-A METHOD OF DETERMINATION OF SERUM TRIGLYCERIDES AND REAGENTS LATRON LABORATORIES, INC. (JA) 1977-07-26 US claimed
US-4006061-A Lactate dehydrogenase determination method MONSANTO COMPANY (US) 1977-02-01 US claimed