Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.58 |
| ▸ | PGR | P06401 | 5/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 9/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31295747 | 1.00 | PDK2 (0.58) | PDK2PGRALKABCC9ABCC8 | |
| SCHEMBL18914750 | 0.83 | PGR (0.53) | PDK2PGRALK | |
| SCHEMBL13930414 | 0.83 | PGR (0.45) | PDK2PGRTSHR | |
| SCHEMBL15158548 | 0.83 | PGR (0.45) | PDK2PGR | |
| SCHEMBL18907195 | 0.82 | ALDH1A1 (0.47) | PDK2ALK | |
| SCHEMBL19588872 | 0.82 | PDK2 (0.45) | PDK2PGRALK | |
| SCHEMBL13367369 | 0.82 | PDK2 (0.48) | PDK2PGRALKTSHR | |
| SCHEMBL10039372 | 0.81 | PDK2 (0.61) | PDK2PGRTSHR | |
| SCHEMBL1116174 | 0.81 | PDK2 (0.61) | PDK2PGRTSHR | |
| SCHEMBL31061764 | 0.81 | PDK2 (0.61) | PDK2PGRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121084-A1 | PREPARATION OF NITRILES | MERCK PATENT GMBH (DE) | 2024-06-13 | — | — | WO | disclosed |
| WO-2024121084-A1 | PREPARATION OF NITRILES | MERCK PATENT GMBH (DE) | 2024-06-13 | — | — | WO | disclosed |
| US-20230126850-A1 | HETEROCYCLIC SPIRO COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-04-27 | — | — | US | disclosed |
| US-11545634-B2 | Heterocyclic spiro compounds | MERCK PATENT GMBH (DE) | 2023-01-03 | — | — | US | disclosed |
| US-11005050-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
| EP-3708634-A1 | HETEROCYCLIC SPIRO COMPOUNDS | Merck Patent GmbH (DE) | 2020-09-16 | — | — | EP | disclosed |
| US-10777750-B2 | Heterocyclic spiro compounds | BASF SE (DE) | 2020-09-15 | — | — | US | disclosed |
| US-20200266364-A1 | HETEROCYCLIC SPIRO COMPOUNDS | MERCK PATENT GMBH (DE) | 2020-08-20 | — | — | US | disclosed |
| EP-3083880-B1 | HETEROCYCLIC SPIRO COMPOUNDS | MERCK PATENT GMBH (DE) | 2020-04-01 | — | — | EP | disclosed |
| US-20190051841-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-02-14 | — | — | US | disclosed |
| US-20160308147-A1 | HETEROCYCLIC SPIRO COMPOUNDS | MERCK PATENT GMBH (DE) | 2016-10-20 | — | — | US | disclosed |
| US-20160260907-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE | BEIJING AGLAIA TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2016-09-08 | — | — | US | disclosed |
| US-20160260907-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE | BEIJING AGLAIA TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2016-09-08 | — | — | US | disclosed |
| WO-2015104045-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2015-07-16 | — | — | WO | disclosed |
| WO-2015090504-A2 | HETEROCYCLIC SPIRO COMPOUNDS | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | WO | disclosed |
| US-8008507-B2 | Fluorescent diketopyrrolopyrroles | BASF SE Ludwigshafen (DE) | 2011-08-30 | — | — | US | disclosed |
| EP-1817392-B1 | FLUORESCENT DIKETOPYRROLOPYRROLES | CIBA HOLDING INC (CH) | 2009-01-07 | — | — | EP | disclosed |
| US-20080217581-A1 | Inks, colorants, pigmented plastics for coatings, non-impact-printing material, color filters, cosmetics, polymeric ink particles, toners, fluorescent tracers; high in the efficiency of electrical energy utilisation and high in luminance | CIBA CORPORATION | 2008-09-11 | — | — | US | disclosed |
| EP-1817392-A1 | FLUORESCENT DIKETOPYRROLOPYRROLES | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006061343-A1 | FLUORESCENT DIKETOPYRROLOPYRROLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190051841-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | AOC2, CYP1A1, CRY1 | PDK2 665/4885PGR 1356/4885ALK 1576/4885 |
| US-20160308147-A1 | HETEROCYCLIC SPIRO COMPOUNDS | NES, KCNC1, HCN4 | PDK2 264/4885PGR 1584/4885ALK 3038/4885 |
| US-20160260907-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE | APRT, TTR, ACE | PDK2 1570/4885PGR 497/4885ALK 276/4885 |
| US-11545634-B2 | Heterocyclic spiro compounds | NES, KCNC1, HCN4 | PDK2 264/4885PGR 1584/4885ALK 3038/4885 |
| US-20080217581-A1 | Inks, colorants, pigmented plastics for coatings, non-impact-printing material, color filters, cosmetics, polymeric ink particles, toners, fluorescent tracers; high in the efficiency of electrical energy utilisation and high in luminance | TYR, MC1R, IK | PDK2 31/4885PGR 397/4885ALK 191/4885 |
| US-20200266364-A1 | HETEROCYCLIC SPIRO COMPOUNDS | NES, KCNC1, HCN4 | PDK2 264/4885PGR 1584/4885ALK 3038/4885 |
| US-11005050-B2 | Metal complexes | SOD1, AP1M1, AP3M1 | PDK2 2330/4885PGR 3351/4885ALK 4314/4885 |
| US-20230126850-A1 | HETEROCYCLIC SPIRO COMPOUNDS | NES, KCNC1, HCN4 | PDK2 264/4885PGR 1584/4885ALK 3038/4885 |
| US-10777750-B2 | Heterocyclic spiro compounds | NES, KCNC1, HCN4 | PDK2 264/4885PGR 1584/4885ALK 3038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.