Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10466726 | 0.69 | GPR84 (0.65) | IMPDH2IMPDH1GPR84ALDH1A1MEN1 | |
| SCHEMBL5469781 | 0.68 | PBRM1 (0.51) | GPR84ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL24651224 | 0.66 | GPR84 (0.61) | GPR84ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL5813081 | 0.66 | NTRK1 (0.48) | GPR84ALDH1A1TDP1NTRK1DAPK3 | |
| SCHEMBL5822163 | 0.66 | NTRK1 (0.48) | GPR84ALDH1A1NTRK1DAPK3PRKD3 | |
| SCHEMBL27872853 | 0.66 | GPR84 (0.55) | IMPDH2IMPDH1GPR84ALDH1A1MEN1 | |
| SCHEMBL5468659 | 0.65 | NTRK1 (0.47) | GPR84MEN1MAPTKMT2ANTRK1 | |
| SCHEMBL8336309 | 0.65 | GPR84 (0.53) | IMPDH2IMPDH1GPR84ALDH1A1MEN1 | |
| SCHEMBL17207498 | 0.64 | KIF20A (0.65) | IMPDH2IMPDH1GPR84ALDH1A1MEN1 | |
| SCHEMBL26070596 | 0.64 | ALDH1A1 (0.57) | IMPDH2IMPDH1GPR84ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240293366-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. | 2024-09-05 | — | — | US | disclosed |
| EP-4252844-A2 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. (US) | 2023-10-04 | — | — | EP | disclosed |
| CN-114206312-A | Topical compositions and methods for treating inflammatory skin disorders | 阿佐拉治疗股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| US-20220023259-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. | 2022-01-27 | — | — | US | disclosed |
| US-11154533-B2 | Topical compositions and methods for treating inflammatory skin diseases | AZORA THERAPEUTICS, INC. (US) | 2021-10-26 | — | — | US | disclosed |
| US-20210186931-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210186931-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AHR, ARNT, TLR8 | IMPDH2 439/4885IMPDH1 394/4885GPR84 148/4885 |
| US-11154533-B2 | Topical compositions and methods for treating inflammatory skin diseases | AHR, ARNT, TLR8 | IMPDH2 439/4885IMPDH1 394/4885GPR84 148/4885 |
| US-20240293366-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AHR, ARNT, TLR8 | IMPDH2 439/4885IMPDH1 394/4885GPR84 148/4885 |
| US-20220023259-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AHR, ARNT, TLR8 | IMPDH2 439/4885IMPDH1 394/4885GPR84 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.