Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2353872 | 0.86 | CXCR2 (0.32) | ADRA1D | |
| SCHEMBL2353890 | 0.84 | SLC10A2 (0.37) | NOS3NOS1NOS2ADRA1D | |
| SCHEMBL2356693 | 0.74 | ADRA1D (0.30) | ADRA1D | |
| SCHEMBL2354740 | 0.74 | KDM1A (0.32) | — | |
| SCHEMBL2357436 | 0.74 | VEGFA (0.34) | ADRA1D | |
| SCHEMBL2350862 | 0.72 | CTSL (0.36) | — | |
| SCHEMBL2355589 | 0.71 | ADRA1D (0.40) | ADRA1D | |
| SCHEMBL2357167 | 0.66 | ADRA1D (0.37) | ADRA1D | |
| SCHEMBL2354707 | 0.65 | CA1 (0.41) | NOS3NOS1NOS2ADRA1D | |
| SCHEMBL2355362 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | claimed |
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | disclosed |