SCHEMBL23535532

SCHEMBL23535532

O=C(NCCN1CCOCC1)c1ccc(-c2ncc3cnc(-c4ccccc4)cn23)cc1

nearest known ligand 0.66

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CD274 Q9NZQ7 8/20 0.66
HPGD P15428 1/20 0.66
HPGDS O60760 3/20 0.63
EPHX2 P34913 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16496406 0.82 HPGDS (0.72) CD274HPGDHPGDSEPHX2
SCHEMBL23535503 0.81 FYN (0.53)
SCHEMBL23535577 0.81 FYN (0.48)
SCHEMBL8167646 0.81 CD274 (1.00) CD274HPGDHPGDSEPHX2
SCHEMBL23535596 0.81 RAB9A (0.53) HPGD
SCHEMBL28963626 0.81 FYN (0.48) HPGDS
SCHEMBL23535524 0.80 FYN (0.61)
SCHEMBL23535583 0.79 TSHR (0.53) HPGD
SCHEMBL14082190 0.78 HPGDS (1.00) CD274HPGDHPGDSEPHX2
SCHEMBL28963628 0.77 ATM (0.48) HPGDS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115768757-A CD206 modulators and uses and methods of making thereof 美利坚合众国,由健康及人类服务部部长代表 2023-03-07 CN disclosed
US-20230056497-A1 CD206 Modulators Their Use and Methods for Preparation US HEALTH (US) 2023-02-23 US disclosed
EP-4077297-A1 CD206 MODULATORS THEIR USE AND METHODS FOR PREPARATION The United States Of America, As Represented By The Secretary, Department Of Health And Human Services (US) 2022-10-26 EP disclosed
WO-2021126923-A1 CD206 MODULATORS THEIR USE AND METHODS FOR PREPARATION THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2021-06-24 WO disclosed
WO-2021126923-A1 CD206 MODULATORS THEIR USE AND METHODS FOR PREPARATION THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2021-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230056497-A1 CD206 Modulators Their Use and Methods for Preparation CD209, MSR1, ARG1 CD274 755/4885HPGD 1072/4885HPGDS 182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.