SCHEMBL23535577

SCHEMBL23535577

CC(=O)NCCNC(=O)c1ccc(-c2ncc3cnc(-c4ccccc4)cn23)cc1

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FYN P06241 16/20 0.48
ATM Q13315 1/20 0.48
RAD52 P43351 1/20 0.47
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
GABRA5 P31644 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28963628 0.92 ATM (0.48) FYNATMRAD52
SCHEMBL23535596 0.88 RAB9A (0.53) FYNATMRAD52RAB9AGABRA5
SCHEMBL23535507 0.88 FYN (0.48) FYNMAPT
SCHEMBL23535524 0.88 FYN (0.61) FYNRAD52
SCHEMBL23535503 0.87 FYN (0.53) FYNATMRAD52
SCHEMBL28963626 0.86 FYN (0.48) FYNATMRAD52
SCHEMBL23535481 0.83 CACNA1B (0.52) ATMMAPT
SCHEMBL23535506 0.81 CYP3A4 (0.59) FYN
SCHEMBL23535532 0.81 CD274 (0.66)
SCHEMBL23535588 0.80 LDHA (0.53) ATMMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115768757-A CD206 modulators and uses and methods of making thereof 美利坚合众国,由健康及人类服务部部长代表 2023-03-07 CN disclosed
US-20230056497-A1 CD206 Modulators Their Use and Methods for Preparation US HEALTH (US) 2023-02-23 US disclosed
EP-4077297-A1 CD206 MODULATORS THEIR USE AND METHODS FOR PREPARATION The United States Of America, As Represented By The Secretary, Department Of Health And Human Services (US) 2022-10-26 EP disclosed
WO-2021126923-A1 CD206 MODULATORS THEIR USE AND METHODS FOR PREPARATION THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2021-06-24 WO disclosed
WO-2021126923-A1 CD206 MODULATORS THEIR USE AND METHODS FOR PREPARATION THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2021-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230056497-A1 CD206 Modulators Their Use and Methods for Preparation CD209, MSR1, ARG1 FYN 1874/4885ATM 3092/4885RAD52 3950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.