Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 17/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23570345 | 0.77 | ALDH1A1 (0.44) | HSD11B1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL23536536 | 0.77 | HSD11B1 (0.40) | HSD11B1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL23536736 | 0.73 | PDE4A (0.37) | HSD11B1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL23536561 | 0.70 | RORC (0.36) | HSD11B1ALDH1A1 | |
| SCHEMBL3212746 | 0.68 | HSD11B1 (0.76) | HSD11B1MEN1KMT2ATDP1GBA1 | |
| SCHEMBL31713632 | 0.68 | HSD11B1 (0.38) | HSD11B1KMT2AALDH1A1HPGDHTT | |
| SCHEMBL23570175 | 0.67 | HTR6 (0.63) | — | |
| SCHEMBL23536541 | 0.67 | RORC (0.37) | HSD11B1 | |
| SCHEMBL31713402 | 0.66 | ABL1 (0.38) | HSD11B1KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL31713696 | 0.66 | ABL1 (0.36) | HSD11B1ALDH1A1HPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |