Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | GLP1R | P43220 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKLR | P30613 | 8/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23570345 | 0.73 | ALDH1A1 (0.44) | ALDH1A1HSD11B1MAPTHTR1ADRD2 | |
| SCHEMBL23536616 | 0.73 | ALDH1A1 (0.41) | ALDH1A1MAPTHTR6 | |
| SCHEMBL23536541 | 0.73 | RORC (0.37) | RORCHSD11B1HCRTR1MAPTPDE4A | |
| SCHEMBL23536756 | 0.71 | LMNA (0.35) | RORCALDH1A1HSD11B1HCRTR1MAPT | |
| SCHEMBL23536626 | 0.70 | HSD11B1 (0.46) | ALDH1A1HSD11B1 | |
| SCHEMBL23536536 | 0.67 | HSD11B1 (0.40) | RORCALDH1A1HSD11B1HCRTR1MAPT | |
| SCHEMBL23536641 | 0.65 | HTT (0.46) | ALDH1A1MAPTHTR6 | |
| SCHEMBL23570175 | 0.63 | HTR6 (0.63) | HTR1ADRD2HTR7HTR6 | |
| SCHEMBL23536619 | 0.62 | TP53 (0.34) | ALDH1A1MAPTHTR6 | |
| SCHEMBL23536675 | 0.61 | HSD11B1 (0.39) | RORCALDH1A1HSD11B1MAPTPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |