Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536596 | 0.84 | SLC6A2 (0.39) | SMN1; SMN2TSHRCCR1LMNATP53 | |
| SCHEMBL23536585 | 0.82 | LMNA (0.34) | SMN1; SMN2CCR1LMNATP53GAA | |
| SCHEMBL23536772 | 0.79 | LMNA (0.39) | SMN1; SMN2LMNATP53CYP3A4GBA1 | |
| SCHEMBL23536619 | 0.78 | TP53 (0.34) | SMN1; SMN2CCR1LMNATP53GAA | |
| SCHEMBL23536524 | 0.77 | SMN1; SMN2 (0.36) | SMN1; SMN2TSHRLMNATP53GAA | |
| SCHEMBL23536839 | 0.77 | HSD17B10 (0.39) | SMN1; SMN2TSHRLMNAHTR6CYP3A4 | |
| SCHEMBL23536667 | 0.76 | LMNA (0.34) | SMN1; SMN2CCR1LMNATP53GAA | |
| SCHEMBL23536635 | 0.76 | HSD17B10 (0.48) | TSHRLMNAGAAHTTHTR6 | |
| SCHEMBL23536682 | 0.75 | HTR6 (0.34) | LMNAGAAHTR6CYP2D6PTGDR2 | |
| SCHEMBL23536533 | 0.74 | HTR6 (0.40) | DRD3LMNAHTR6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |