Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29932037 | 0.80 | MCOLN2 (0.37) | — | |
| SCHEMBL23536524 | 0.76 | SMN1; SMN2 (0.36) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL29932142 | 0.75 | PDE4B (0.33) | DRD2 | |
| SCHEMBL23536538 | 0.73 | HTR6 (0.56) | HTR6CYP3A4CYP2D6KLK7 | |
| SCHEMBL4671213 | 0.73 | HTR6 (0.87) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL23536663 | 0.72 | HTR6 (0.46) | HTR6CYP3A4CYP2D6DRD2 | |
| SCHEMBL23536756 | 0.69 | LMNA (0.35) | HTR6 | |
| SCHEMBL6529782 | 0.69 | HTR6 (1.00) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL6530539 | 0.69 | HTR6 (1.00) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5253626 | 0.69 | HTR6 (1.00) | HTR6CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |