Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.35 |
| ▸ | NQO2 | P16083 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2354010 | 0.91 | MMP2 (0.44) | MMP2MMP8SMN1; SMN2ALDH1A1HTR2C | |
| SCHEMBL2353944 | 0.81 | GRIA2 (0.44) | SMN1; SMN2MTNR1AMTNR1BADRA1D | |
| SCHEMBL2351722 | 0.77 | MAOA (0.35) | MAPTADRA1D | |
| SCHEMBL2352846 | 0.77 | ADRA1D (0.42) | MMP2ALDH1A1ADRA1D | |
| SCHEMBL2353940 | 0.76 | GRIA2 (0.48) | SMN1; SMN2RAB9ANPC1MTNR1AMTNR1B | |
| SCHEMBL4803634 | 0.67 | KDM4E (0.47) | MMP2MMP8SMN1; SMN2ALDH1A1HTR2C | |
| SCHEMBL2851912 | 0.67 | MAPK14 (0.64) | MMP2MMP8SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL885045 | 0.65 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1RAB9ANPC1MTNR1A | |
| SCHEMBL2347270 | 0.65 | GRIA1 (0.35) | ALDH1A1HTR2CRAB9ANPC1ADRA1D | |
| SCHEMBL5681744 | 0.64 | PTPN1 (0.56) | SMN1; SMN2ALDH1A1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | disclosed |