Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 5/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2353940 | 0.92 | GRIA2 (0.48) | GRIA2ADRA1DMTNR1AMTNR1BSLC10A2 | |
| SCHEMBL2353218 | 0.92 | ADRA1D (0.46) | GRIA2ADRA1DSLC10A2ABCC8KCNJ11 | |
| SCHEMBL2356821 | 0.91 | GRIA2 (0.44) | GRIA2ADRA1DSLC10A2ADAMTS5 | |
| SCHEMBL2351722 | 0.88 | MAOA (0.35) | GRIA2ADRA1D | |
| SCHEMBL2352846 | 0.88 | ADRA1D (0.42) | GRIA2ADRA1DSLC10A2 | |
| SCHEMBL2353968 | 0.86 | GRIA2 (0.47) | GRIA2ADRA1D | |
| SCHEMBL2357409 | 0.83 | GRIA2 (0.35) | GRIA2ADRA1DSLC10A2SMN1; SMN2 | |
| SCHEMBL2354007 | 0.81 | MMP2 (0.46) | ADRA1DMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL2354383 | 0.77 | CA1 (0.36) | GRIA2ADRA1DSMN1; SMN2CA2 | |
| SCHEMBL2355589 | 0.74 | ADRA1D (0.40) | GRIA2ADRA1DABCC8KCNJ11CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | claimed |
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | disclosed |