Sugi Predict

Sugi Predict / Compounds / SCHEMBL2355648

SCHEMBL2355648

SCHEMBL2355648

[CH2]c1ccccc1-c1ccc(OC)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABL1 P00519 2/20 0.60
▸ ABCB1 P08183 2/20 0.60
▸ BCR P11274 2/20 0.60
▸ HDAC4 P56524 1/20 0.53
▸ HDAC2 Q92769 1/20 0.53
▸ HDAC8 Q9BY41 1/20 0.53
▸ BACE1 P56817 1/20 0.49
▸ PTPN1 P18031 1/20 0.47
▸ HTR1A P08908 1/20 0.46
▸ HTR7 P34969 1/20 0.46
▸ CA4 P22748 1/20 0.46
▸ MAPT P10636 2/20 0.46
▸ NPC1 O15118 1/20 0.46
▸ TP53 P04637 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ CA12 O43570 1/20 0.46
▸ CA1 P00915 1/20 0.46
▸ CA2 P00918 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3230744 0.87 ABL1 (0.51) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL12715050 0.84 ABL1 (0.79) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL2032366 0.82 ABL1 (0.50) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL11096260 0.82 ABL1 (0.76) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL8416898 0.82 ALDH1A1 (0.38) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL2098600 0.82 ABL1 (0.63) ABL1ABCB1BCRCA4MAPT
SCHEMBL11819228 0.80 ABL1 (0.73) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL967992 0.79 BRD4 (0.49) ABL1ABCB1BCRHDAC4HDAC8
SCHEMBL13211660 0.78 ABL1 (0.84) ABL1ABCB1BCRHDAC4HDAC2
Hydrogen Sulfide SCHEMBL27457713 0.78 ABL1 (0.70) ABL1ABCB1BCRHDAC4HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024005039-A1 METHOD FOR PRODUCING VERY-LONG-CHAIN POLYUNSATURATED FATTY ACID 株式会社ニッスイ 2024-01-04 — — WO claimed
EP-2560982-A2 PHOSPHORAMIDITES FOR SYNTHETIC RNA IN THE REVERSE DIRECTION Chemgenes Corporation (US) 2013-02-27 — — EP claimed
WO-2011103468-A2 PHOSPHORAMIDITES FOR SYNTHETIC RNA IN THE REVERSE DIRECTION CHEMGENES CORPORATION (US) 2011-08-25 — — WO claimed
US-20100298392-A1 Isoindoline Derivatives For The Treatment Of Arrhythmias ASTRAZENECA AB (SE) 2010-11-25 — — US claimed
EP-2049484-A1 ISOINDOLINE DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIAS AstraZeneca AB (SE) 2009-04-22 — — EP claimed
WO-2008008022-A1 ISOINDOLINE DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIAS ASTRAZENECA AB (SE) 2008-01-17 — — WO claimed
US-20080015237-A1 NEW COMPOUNDS I/418 ASTRAZENECA AB (SE) 2008-01-17 — — US claimed
WO-2024005039-A1 METHOD FOR PRODUCING VERY-LONG-CHAIN POLYUNSATURATED FATTY ACID 株式会社ニッスイ 2024-01-04 — — WO disclosed
EP-4249077-A1 NOVEL ACRIDINIUM SALT AND METHOD FOR PRODUCING SAME Shionogi & Co., Ltd (JP) 2023-09-27 — — EP disclosed
WO-2023176809-A1 METHOD FOR PRODUCING POLYETHYLENE GLYCOL DERIVATIVE 日油株式会社 2023-09-21 — — WO disclosed
US-20230278960-A1 NOVEL ACRIDINIUM SALT AND METHOD FOR PRODUCING SAME SHIONOGI & CO., LTD. (JP) 2023-09-07 — — US disclosed
US-20230040262-A1 STEREOSELECTIVE PROCESS FOR PREPARING SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVES SHIONOGI & CO., LTD. (JP) 2023-02-09 — — US disclosed
CN-113710750-B (meth) acrylic composition, coating material containing same, and cured product 三菱瓦斯化学株式会社 2022-07-12 — — CN disclosed
US-20100298392-A1 Isoindoline Derivatives For The Treatment Of Arrhythmias ASTRAZENECA AB (SE) 2010-11-25 — — US disclosed
EP-2049484-A1 ISOINDOLINE DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIAS AstraZeneca AB (SE) 2009-04-22 — — EP disclosed
WO-2008008022-A1 ISOINDOLINE DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIAS ASTRAZENECA AB (SE) 2008-01-17 — — WO disclosed
US-20080015237-A1 NEW COMPOUNDS I/418 ASTRAZENECA AB (SE) 2008-01-17 — — US disclosed
US-7262212-B2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-08-28 — — US disclosed
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-05-04 — — US disclosed
EP-1555267-A1 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-07-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230278960-A1 NOVEL ACRIDINIUM SALT AND METHOD FOR PRODUCING SAME ATL3, CBR3, CLIC1 ABL1 1988/4885ABCB1 2589/4885BCR 2025/4885
US-20230040262-A1 STEREOSELECTIVE PROCESS FOR PREPARING SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVES RNGTT, CPSF6, RNASEL ABL1 4735/4885ABCB1 3567/4885BCR 4467/4885
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles NR2C2, NR4A3, NR4A2 ABL1 2364/4885ABCB1 2408/4885BCR 616/4885
US-20080015237-A1 NEW COMPOUNDS I/418 KCNH1, KCNH2, KCNH3 ABL1 2396/4885ABCB1 236/4885BCR 2239/4885
US-20100298392-A1 Isoindoline Derivatives For The Treatment Of Arrhythmias KCNH1, KCNH2, KCNQ2 ABL1 1004/4885ABCB1 313/4885BCR 2306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.