SCHEMBL235567

SCHEMBL235567

CC(C)COC(=O)c1ccc(Br)cc1C(=O)OCC(C)C

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.64
TSHR P16473 3/20 0.64
HPGD P15428 4/20 0.48
MAPT P10636 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HTT P42858 2/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.45
TP53 P04637 1/20 0.45
NPY1R P25929 1/20 0.45
NPY2R P49146 1/20 0.45
KMT2A Q03164 1/20 0.45
ATM Q13315 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
MAPK1 P28482 1/20 0.43
THRB P10828 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4627141 0.94 ALDH1A1 (0.57) ALDH1A1TSHRHPGDMAPTSMN1; SMN2
SCHEMBL4628603 0.89 TSHR (0.54) ALDH1A1TSHRHPGDSMN1; SMN2HTT
SCHEMBL20833977 0.86 ALDH1A1 (0.54) ALDH1A1TSHRHPGDMAPTSMN1; SMN2
SCHEMBL15675248 0.84 HPGD (0.46) ALDH1A1TSHRHPGDSMN1; SMN2TDP1
SCHEMBL4628560 0.82 TSHR (0.61) ALDH1A1TSHRMAPTSMN1; SMN2HTT
SCHEMBL9120765 0.82 TSHR (0.50) ALDH1A1TSHRHPGDMAPTSMN1; SMN2
SCHEMBL827863 0.82 TSHR (0.70) ALDH1A1TSHRMAPTSMN1; SMN2HTT
SCHEMBL235910 0.81 ATM (0.44) ALDH1A1TSHRHPGDHTTTDP1
SCHEMBL301540 0.81 ALDH1A1 (0.66) ALDH1A1TSHRMAPTSMN1; SMN2HTT
SCHEMBL828419 0.81 ALDH1A1 (0.66) ALDH1A1TSHRMAPTSMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115926331-B Polybutene-1 alloy and preparation method thereof 中国石油天然气股份有限公司 2025-02-11 CN claimed
CN-114805647-B Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2024-03-29 CN claimed
CN-115926331-A Polybutene-1 alloy and preparation method thereof 中国石油天然气股份有限公司 2023-04-07 CN claimed
CN-114805647-A Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2022-07-29 CN claimed
US-6770586-B2 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD. (JP) 2004-08-03 US claimed
CN-115926331-B Polybutene-1 alloy and preparation method thereof 中国石油天然气股份有限公司 2025-02-11 CN disclosed
US-12060378-B2 Solid catalyst component for olefin polymerization, method for producing solid catalyst component for olefin polymerization, method for producing catalyst for olefin polymerization and method for producing polymer of olefin TOHO TITANIUM CO., LTD. (JP) 2024-08-13 US disclosed
US-20240218087-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, METHOD FOR PRODUCING POLYMER OF OLEFIN, POLYMER OF OLEFIN, METHOD FOR PRODUCING PROPYLENE-BASED BLOCK COPOLYMER, AND PROPYLENE-BASED BLOCK COPOLYMER TOHO TITANIUM CO., LTD. (JP) 2024-07-04 US disclosed
EP-4349874-A1 OLEFIN POLYMERIZATION SOLID CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, MANUFACTURING METHOD FOR OLEFIN POLYMER, OLEFIN POLYMER, MANUFACTURING METHOD FOR PROPYLENE-BASED BLOCK COPOLYMER, AND PROPYLENE-BASED BLOCK COPOLYMER TOHO TITANIUM CO., LTD. (JP) 2024-04-10 EP disclosed
CN-114805647-B Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2024-03-29 CN disclosed
EP-3645625-B1 HIGH STIFFNESS POLYPROPYLENE IMPACT COPOLYMER EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-03-27 EP disclosed
CN-117425682-A Solid catalyst component for olefin polymerization, catalyst for olefin polymerization, process for producing olefin polymer, process for producing propylene block copolymer, and propylene block copolymer 东邦钛株式会社 2024-01-19 CN disclosed
US-20040077488-A1 Polymerization catalyst for olefins and process for polymerization of olefins TOHO TITANIUM CO., LTD. (JP) 2004-04-22 US disclosed
US-6670497-B2 Dialkyl (at least one of which is a C4-8 tertiary alkyl) ester of an alkyl- or halo-substituted phthalic acid; used in an olefin polymerization catalyst TOHO TITANIUM CO., LTD. (JP) 2003-12-30 US disclosed
US-20030153454-A1 Solid catalyst ingredient and catalyst each for olefin polymerization and propylene block copolymer TOHO TITANIUM CO., LTD. (JP) 2003-08-14 US disclosed
US-20030130109-A1 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD (JP) 2003-07-10 US disclosed
US-20030036594-A1 Phthalic diester derivatives and electron donors TOHO TITANIUM CO., LTD. (JP) 2003-02-20 US disclosed
EP-1283222-A1 SOLID CATALYST INGREDIENT AND CATALYST EACH FOR OLEFIN POLYMERIZATION AND PROPYLENE BLOCK COPOLYMER Toho Catalyst Co., Ltd. (JP) 2003-02-12 EP disclosed
EP-1209172-A1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2002-05-29 EP disclosed
EP-1188739-A1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO., LTD. (JP) 2002-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12060378-B2 Solid catalyst component for olefin polymerization, method for producing solid catalyst component for olefin polymerization, method for producing catalyst for olefin polymerization and method for producing polymer of olefin EEF2, ELL, POF1B ALDH1A1 3897/4885TSHR 3311/4885HPGD 909/4885
US-20030036594-A1 Phthalic diester derivatives and electron donors HPD, ETFA, PPOX ALDH1A1 725/4885TSHR 4817/4885HPGD 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.