SCHEMBL2355804

SCHEMBL2355804

N#Cc1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.53
MAPT P10636 2/20 0.53
HPGD P15428 2/20 0.53
ALDH1A1 P00352 2/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
KDM4E B2RXH2 1/20 0.53
LMNA P02545 1/20 0.53
TRPA1 O75762 1/20 0.51
SRD5A2 P31213 1/20 0.47
PDK2 Q15119 1/20 0.45
CYP1A2 P05177 3/20 0.45
CYP3A4 P08684 2/20 0.45
DRD2 P14416 3/20 0.44
DRD3 P35462 2/20 0.44
PNMT P11086 1/20 0.44
HSD17B10 Q99714 2/20 0.43
MAOA P21397 2/20 0.42
HTR2C P28335 2/20 0.42
HTR2B P41595 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31441011 1.00 SMN1; SMN2 (0.53) SMN1; SMN2MAPTHPGDALDH1A1NPC1
SCHEMBL17242315 0.92 TRPA1 (0.51) SMN1; SMN2MAPTHPGDALDH1A1NPC1
SCHEMBL30950987 0.90 PNMT (0.52) TRPA1PDK2DRD2DRD3PNMT
SCHEMBL6014131 0.90 PNMT (0.52) TRPA1PDK2DRD2DRD3PNMT
SCHEMBL11678763 0.88 PNMT (0.47) SMN1; SMN2MAPTHPGDALDH1A1NPC1
SCHEMBL28246117 0.86 PDK2 (0.50) SMN1; SMN2MAPTHPGDALDH1A1NPC1
SCHEMBL10052973 0.83 TRPA1 (0.44) SMN1; SMN2MAPTHPGDALDH1A1NPC1
SCHEMBL31739245 0.82 TSHR (0.47) SMN1; SMN2MAPTHPGDALDH1A1NPC1
SCHEMBL11676256 0.81 PNMT (0.47) ALDH1A1TRPA1DRD2DRD3PNMT
SCHEMBL739759 0.81 SMN1; SMN2 (0.53) SMN1; SMN2MAPTHPGDALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260150499-A1 Organic Compounds and Electroluminescent Device Comprising the Same P&H TECH CO., LTD (KR) 2026-05-28 US disclosed
US-20260093180-A1 METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE AND COMPOSITION FOR FILM FORMATION JSR CORPORATION (JP) 2026-04-02 US disclosed
US-20250346585-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2025-11-13 US disclosed
CN-119219454-A Method for preparing aromatic nitrile compound by photoinitiating nitroarene denitration cyanation 武汉光化学技术研究院 2024-12-31 CN disclosed
CN-117903077-B Dihydrooxadiazinone compound and application thereof 上海超阳药业有限公司 2024-09-03 CN disclosed
WO-2024136541-A1 ORGANIC LUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 솔루스첨단소재 주식회사 2024-06-27 WO disclosed
CN-117903077-A Dihydrooxadiazinon compound and application thereof 上海超阳药业有限公司 2024-04-19 CN disclosed
WO-2024034311-A1 SEMICONDUCTOR SUBSTRATE PRODUCTION METHOD AND FILM FORMING COMPOSITION JSR株式会社 2024-02-15 WO disclosed
WO-2023183405-A2 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2023-09-28 WO disclosed
WO-2023183405-A2 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2023-09-28 WO disclosed
EP-1817392-A1 FLUORESCENT DIKETOPYRROLOPYRROLES Ciba Specialty Chemicals Holding Inc. (CH) 2007-08-15 EP disclosed
WO-2006061343-A1 FLUORESCENT DIKETOPYRROLOPYRROLES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-06-15 WO disclosed
EP-0400972-B1 Fluorescent degree of cure monitors MINNESOTA MINING & MFG (US) 1996-07-03 EP disclosed
US-5182316-A Forming a UV-detectable fluorophore in a mixture of hydride containing silicone, unsaturated silicone, cationically sensitive compound and a latent dibenzofulvene MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-01-26 US disclosed
US-5118559-A Dibenzofulvene compound MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-06-02 US disclosed
US-5047444-A Hydrosilatable polysiloxanes, unsaturated compounds and a dibenzofulvene chromogen; coatings MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-09-10 US disclosed
EP-0400972-A2 Fluorescent degree of cure monitors MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-12-05 EP disclosed
US-4656233-A \"Living\" polymers and chain transfer-regulated polymerization process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-04-07 US disclosed
EP-0186330-A1 \"Living\" polymers and chain transfer-regulated polymerization process E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-07-02 EP disclosed
US-4189323-A Radiation-sensitive copying composition HOECHST AKTIENGESELLSCHAFT (DE) 1980-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260093180-A1 METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE AND COMPOSITION FOR FILM FORMATION SMC4, TYR, SMC2 SMN1; SMN2 1676/4885MAPT 1281/4885HPGD 4696/4885
US-20250346585-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS C5, C1S, C9 SMN1; SMN2 266/4885MAPT 1464/4885HPGD 1644/4885
US-20260150499-A1 Organic Compounds and Electroluminescent Device Comprising the Same CRY2, NOX1, NOX4 SMN1; SMN2 1086/4885MAPT 3974/4885HPGD 3739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.