Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356948 | 0.82 | PRSS1 (0.42) | RAB9AALDH1A1LMNAKMT2A | |
| SCHEMBL6027320 | 0.80 | ELANE (0.44) | RAB9AALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL28068262 | 0.80 | NPC1 (0.55) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4327858 | 0.78 | HDAC1 (0.35) | SMN1; SMN2LMNA | |
| SCHEMBL16856755 | 0.77 | SMN1; SMN2 (0.55) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8581687 | 0.77 | PTPN2 (0.36) | PTPN1 | |
| SCHEMBL16670075 | 0.77 | RAB9A (0.40) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29459735 | 0.77 | CES2 (0.65) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL777802 | 0.77 | CES2 (0.65) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2292815 | 0.76 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7057035-B2 | N-hydroxysuccinimide process for conversion of phenols to carboxamides | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2006-06-06 | — | — | US | disclosed |
| US-20050215799-A1 | N-hydroxysuccinimide process for conversion of phenols to carboxamides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-09-29 | — | — | US | disclosed |
| WO-2004007449-A1 | PROCESS FOR CONVERSION OF PHENOLS TO CARBOXAMIDES VIA THE SUCCINIMIDE ESTERS | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215799-A1 | N-hydroxysuccinimide process for conversion of phenols to carboxamides | HNMT, HAAO, CPS1 | CES2 332/4885CES1 2654/4885NPC1 3872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.