Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356948 | 0.94 | PRSS1 (0.42) | ALDH1A1PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL9244293 | 0.86 | AKR1C3 (0.44) | ELANEALDH1A1CA1CA2CA9 | |
| SCHEMBL8581687 | 0.82 | PTPN2 (0.36) | CA1CA2 | |
| SCHEMBL16670075 | 0.82 | RAB9A (0.40) | CA1CA2LMNARAB9AATM | |
| SCHEMBL9318015 | 0.80 | LMNA (0.56) | ALDH1A1PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL5986576 | 0.80 | CES2 (0.44) | ALDH1A1LMNAHPGDRAB9AMEN1 | |
| SCHEMBL3111477 | 0.79 | CA1 (0.41) | CA12CA1CA2CA9CA14 | |
| SCHEMBL16553458 | 0.79 | ALDH1A1 (0.46) | ALDH1A1RAB9AMAPTKMT2A | |
| SCHEMBL15515208 | 0.79 | ELANE (0.46) | ELANEALDH1A1SRD5A2PPARAPRSS1 | |
| Water SCHEMBL21440321 | 0.79 | LMNA (0.54) | ALDH1A1PRSS1CTSGCTRB1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141394-B2 | More stable analog of isopropyl thiogalactoside for induction of protein expression | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-11-28 | — | — | US | disclosed |
| US-20040224390-A1 | More stable analog of isopropylthiogalactoside for induction of protein expression | IOWA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2004-11-11 | — | — | US | disclosed |
| WO-2004094445-A1 | A MORE STABLE ANALOG OF ISO-PROPYLTHIOGALACTOSIDE FOR INDUCTION OF PROTEIN EXPRESSION | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC (US) | 2004-11-04 | — | — | WO | disclosed |
| US-5587509-A | Caged caboxyl compounds and use thereof | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-12-24 | — | — | US | disclosed |
| WO-1995015305-A1 | CAGED CARVOXYL COMPOUNDS AND THEIR USE IN CHEMICAL KINETIC INVESTIGATION OF NEUROTRANSMITTER RECEPTORS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1995-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224390-A1 | More stable analog of isopropylthiogalactoside for induction of protein expression | PPIG, B3GAT3, PPIC | ELANE 3391/4885ALDH1A1 3670/4885SRD5A2 4110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.